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In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection
http://hdl.handle.net/10069/33918
http://hdl.handle.net/10069/339188065df2f-566e-45b4-9c8d-23ea51918c32
名前 / ファイル | ライセンス | アクション |
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AAC57_2841.pdf (920.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-01-01 | |||||
タイトル | ||||||
タイトル | In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | daptomycin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | methicillin-resistant Staphylococcus aureus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hematogenous | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pulmonary infection | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Harada, Yosuke
× Harada, Yosuke× Yanagihara, Katsunori× Yamada, Koichi× Migiyama, Yohei× Nagaoka, Kentaro× Morinaga, Yoshitomo× Nakamura, Shigeki× Imamura, Yoshifumi× Hasegawa, Hiroo× Miyazaki, Taiga× Izumikawa, Koichi× Kakeya, Hiroshi× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous pulmonary infection mouse model. Compared with control results, daptomycin improved survival (P<0.001) and decreased the number of abscesses and bacteria in the lungs (P<0.01). Daptomycin may be an effective therapeutic option for MRSA hematogenous pulmonary infection. | |||||
書誌情報 |
Antimicrobial Agents and Chemotherapy 巻 57, 号 6, p. 2841-2844, 発行日 2013-06 |
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出版者 | ||||||
出版者 | American Society for Microbiology | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00664804 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 10986596 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1128/AAC.02331-12 | |||||
権利 | ||||||
権利情報 | © 2013, American Society for Microbiology. All Rights Reserved. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Antimicrobial Agents and Chemotherapy, 57(6), pp.2841-2844; 2013 |