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Characteristics of gastrointestinal symptoms and function following endoscopic submucosal dissection and treatment of the gastrointestinal symptoms using rikkunshito
http://hdl.handle.net/10069/33955
http://hdl.handle.net/10069/3395525af0e25-3467-466d-abe9-f88acee45366
名前 / ファイル | ライセンス | アクション |
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ETM6_1083.pdf (542.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-06-01 | |||||
タイトル | ||||||
タイトル | Characteristics of gastrointestinal symptoms and function following endoscopic submucosal dissection and treatment of the gastrointestinal symptoms using rikkunshito | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Abdominal pain | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Endoscopic submucosal dissection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gastric cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gastric emptying | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rikkunshito | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Uehara, Ryohei
× Uehara, Ryohei× Isomoto, Hajime× Minami, Hitomi× Yamaguchi, Naoyuki× Ohnita, Ken× Ichikawa, Tatsuki× Takeshima, Fuminao× Shikuwa, Saburo× Nakao, Kazuhiko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of the present study was to investigate the gastrointestinal (GI) symptoms and gastric emptying following endoscopic submucosal dissection (ESD), as well as to evaluate a novel treatment strategy using rikkunshito, a traditional Japanese herbal medicine. GI symptoms and gastric emptying were evaluated 6-8 days after ESD as part of the Step I study. In the Step 1 study, the Gastrointestinal Symptom Rating Scale (GSRS) scores of the two groups after 4 and 8 weeks of treatment with either a proton pump inhibitor (PPI; PPI monotreatment group, n=5) or a PPI plus rikkunshito (PPI + rikkunshito group, n=8) were compared against baseline values. Abdominal pain and constipation occurred in the majority of patients after ESD. The mean T-max 6-8 days after gastric emptying was 75.4±13.6 min, which was significantly longer compared with that reported in healthy subjects (43.9±10.3 min). In the Step 2 study, the total GSRS score was significantly improved only in the PPI + rikkunshito group after 8 weeks of treatment. In conclusion, ESD affects gastric emptying and is associated with an increased incidence of upper GI symptoms such as abdominal pain and indigestion. Rikkunshito may be useful as a novel supporting therapeutic drug for the treatment of GI symptoms in patients who have undergone ESD. | |||||
書誌情報 |
Experimental and Therapeutic Medicine 巻 6, 号 5, p. 1083-1088, 発行日 2013-11 |
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出版者 | ||||||
出版者 | Spandidos Publications | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 17920981 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 17921015 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3892/etm.2013.1299 | |||||
権利 | ||||||
権利情報 | © Spandidos Publications 2013. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Experimental and Therapeutic Medicine, 6(5), pp.1083-1088; 2013 |