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Changes in Hind Paw Epidermal Thickness, Peripheral Nerve Distribution and Mechanical Sensitivity After Immobilization in Rats
http://hdl.handle.net/10069/31973
http://hdl.handle.net/10069/3197365742df3-b28f-4e0d-ab45-4caf2418b230
名前 / ファイル | ライセンス | アクション |
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PhyRes61_643.pdf (1.7 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-05-27 | |||||
タイトル | ||||||
タイトル | Changes in Hind Paw Epidermal Thickness, Peripheral Nerve Distribution and Mechanical Sensitivity After Immobilization in Rats | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epidermal thickness | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hypersensitivity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Immobilization | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Peripheral nerve | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Skin | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nakano, Jiro
× Nakano, Jiro× Sekino, Y× Hamaue, Y× Sakamoto, Junya× Yoshimura, T× Origuchi, Tomoki× Okita, Minoru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | This study was designed to investigate histological changes in skin tissue accompanying immobilization-induced hypersensitivity. Changes in mechanical sensitivity, epidermal thickness, and peripheral nerve profiles in the upper dermis were examined in glabrous skin of rat hind paw after 1, 2, and 4 weeks of ankle joint immobilization by plaster casts. Induction of mechanical hypersensitivity was confirmed after 2 and 4 weeks of joint immobilization. Epidermal thinning and increase in peripheral nerve profiles were observed in skin tissues in immobilized rats. The time course of epidermal thinning and increase in peripheral nerve profiles were similar closely to that of hypersensitivity, with significant differences between the immobilized and control rats after 2 weeks of immobilization, which became even more remarkable at 4 weeks of immobilization. These findings suggest that joint immobilization by cast induces epidermal thinning and increases peripheral nerve profiles in the upper dermis and that these changes might be partly responsible for immobilization-induced hypersensitivity. | |||||
書誌情報 |
PHYSIOLOGICAL RESEARCH 巻 61, 号 6, p. 643-647, 発行日 2012 |
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出版者 | ||||||
出版者 | Czech Academy of Sciences | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18029973 | |||||
権利 | ||||||
権利情報 | © 2012 Institute of Physiology v.v.i., Academy of Sciences of the Czech Republic, Prague, Czech Republic | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PHYSIOLOGICAL RESEARCH, 61(6), pp.643-647; 2012 |