WEKO3
アイテム
{"_buckets": {"deposit": "339bfe8a-a9c5-4d9e-aeb2-67ad5fd7ce18"}, "_deposit": {"created_by": 2, "id": "9304", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "9304"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00009304", "sets": ["74"]}, "author_link": ["37396", "37395", "37394", "37398", "37397"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "9", "bibliographicPageEnd": "2770", "bibliographicPageStart": "2765", "bibliographicVolumeNumber": "403", "bibliographic_titles": [{"bibliographic_title": "Analytical and Bioanalytical Chemistry"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The Petasis reaction is the multi-component reaction of a carbonyl compound, amine, and arylboronic acid to form an α-amino acid or a β-aminoalcohol. In this work, as the first analytical application of the Petasis reaction, a highperformance liquid chromatographic (HPLC) method with fluorescence detection was developed for determination of glyoxylic acid. The glyoxylic acid was derivatized with 1- pyreneboronic acid, as fluorescent arylboronic acid, in the presence of N-methylbutylamine, as amine, to give a fluorescent α-amino acid. HPLC separation of the fluorescent derivative was performed within 30 min on an octyl column eluted with a gradient prepared from acetonitrile and 50 mmol L -1 acetate buffer (pH 4.0). The detection limit (S/N03) for glyoxylic acid was 5.0 nmol L -1 (20 fmol/injection). The method can be used to determine the concentration of glyoxylic acid in human urine without interference from biological components.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Analytical and Bioanalytical Chemistry, 403(9), pp.2765-2770; 2012", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Springer Verlag"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/s00216-012-6036-1", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© Springer-Verlag 2012."}, {"subitem_rights": "The final publication is available at www.springerlink.com."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "16182642", "subitem_source_identifier_type": "ISSN"}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "16182650", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Chihara, Kohki"}], "nameIdentifiers": [{"nameIdentifier": "37394", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kishikawa, Naoya"}], "nameIdentifiers": [{"nameIdentifier": "37395", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohyama, Kaname"}], "nameIdentifiers": [{"nameIdentifier": "37396", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakashima, Kenichiro"}], "nameIdentifiers": [{"nameIdentifier": "37397", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kuroda, Naotaka"}], "nameIdentifiers": [{"nameIdentifier": "37398", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ABC403_2765.pdf", "filesize": [{"value": "226.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 226500.0, "url": {"label": "ABC403_2765.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/9304/files/ABC403_2765.pdf"}, "version_id": "172c24e3-3b56-46a2-b2e1-c7ff71df90c4"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Acetate buffers", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Amino alcohols", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Analytical applications", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Arylboronic acids", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Biological components", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Derivatization procedures", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Detection limits", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Fluorescence derivatization", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Fluorescence detection", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Glyoxylic acids", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HPLC separation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Human urine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Multi-component reactions", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Petasis reaction", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Determination of glyoxylic acid in urine by liquid chromatography with fluorescence detection, using a novel derivatization procedure based on the Petasis reaction", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Determination of glyoxylic acid in urine by liquid chromatography with fluorescence detection, using a novel derivatization procedure based on the Petasis reaction"}]}, "item_type_id": "2", "owner": "2", "path": ["74"], "permalink_uri": "http://hdl.handle.net/10069/29900", "pubdate": {"attribute_name": "公開日", "attribute_value": "2012-11-30"}, "publish_date": "2012-11-30", "publish_status": "0", "recid": "9304", "relation": {}, "relation_version_is_last": true, "title": ["Determination of glyoxylic acid in urine by liquid chromatography with fluorescence detection, using a novel derivatization procedure based on the Petasis reaction"], "weko_shared_id": -1}
Determination of glyoxylic acid in urine by liquid chromatography with fluorescence detection, using a novel derivatization procedure based on the Petasis reaction
http://hdl.handle.net/10069/29900
http://hdl.handle.net/10069/2990020366a65-0c7a-4630-b119-b7717873b9f0
名前 / ファイル | ライセンス | アクション |
---|---|---|
ABC403_2765.pdf (226.5 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2012-11-30 | |||||
タイトル | ||||||
タイトル | Determination of glyoxylic acid in urine by liquid chromatography with fluorescence detection, using a novel derivatization procedure based on the Petasis reaction | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Acetate buffers | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Amino alcohols | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Analytical applications | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Arylboronic acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Biological components | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Derivatization procedures | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Detection limits | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Fluorescence derivatization | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Fluorescence detection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Glyoxylic acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HPLC separation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Human urine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Multi-component reactions | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Petasis reaction | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Chihara, Kohki
× Chihara, Kohki× Kishikawa, Naoya× Ohyama, Kaname× Nakashima, Kenichiro× Kuroda, Naotaka |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The Petasis reaction is the multi-component reaction of a carbonyl compound, amine, and arylboronic acid to form an α-amino acid or a β-aminoalcohol. In this work, as the first analytical application of the Petasis reaction, a highperformance liquid chromatographic (HPLC) method with fluorescence detection was developed for determination of glyoxylic acid. The glyoxylic acid was derivatized with 1- pyreneboronic acid, as fluorescent arylboronic acid, in the presence of N-methylbutylamine, as amine, to give a fluorescent α-amino acid. HPLC separation of the fluorescent derivative was performed within 30 min on an octyl column eluted with a gradient prepared from acetonitrile and 50 mmol L -1 acetate buffer (pH 4.0). The detection limit (S/N03) for glyoxylic acid was 5.0 nmol L -1 (20 fmol/injection). The method can be used to determine the concentration of glyoxylic acid in human urine without interference from biological components. | |||||
書誌情報 |
Analytical and Bioanalytical Chemistry 巻 403, 号 9, p. 2765-2770, 発行日 2012-07 |
|||||
出版者 | ||||||
出版者 | Springer Verlag | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 16182642 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 16182650 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s00216-012-6036-1 | |||||
権利 | ||||||
権利情報 | © Springer-Verlag 2012. | |||||
権利 | ||||||
権利情報 | The final publication is available at www.springerlink.com. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Analytical and Bioanalytical Chemistry, 403(9), pp.2765-2770; 2012 |