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Clinicopathological risk factors for local recurrence in oral squamous cell carcinoma
http://hdl.handle.net/10069/30254
http://hdl.handle.net/10069/302544430106c-40bb-4986-aa02-8c4a9122331a
名前 / ファイル | ライセンス | アクション |
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IJOMS41_1195.pdf (400.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-01-17 | |||||
タイトル | ||||||
タイトル | Clinicopathological risk factors for local recurrence in oral squamous cell carcinoma | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | local recurrence | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | neoadjuvant chemotherapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | oral squamous cell carcinoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | surgical margin | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yanamoto, Souichi
× Yanamoto, Souichi× Yamada, Shinichi× Takahashi, Hidenori× Yoshitomi, Izumi× Kawasaki, Goro× Ikeda, Hisazumi× Minamizato, Tokutarou× Shiraishi, Takeshi× Fujita, Shuichi× Ikeda, Tohru× Asahina, Izumi× Umeda, Masahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Local recurrence of oral squamous cell carcinoma (OSCC) after primary surgery has been considered to be a poor prognostic entity in terms of survival rate. The purpose of this study is to evaluate the incidence of local recurrence and to identify significant risk factors for the local recurrence in OSCC. The authors retrospectively reviewed records for 187 patients who underwent radical surgery for OSCC. The local recurrence rate was 16.0% (30/187 patients) in this study. The survival rate of patients with local recurrence was 33.3%, which was significantly lower than that (94.3%) of patients without local recurrence. Pattern of invasion (POI), neoadjuvant chemotherapy (NAC), and the status of the surgical margin were identified as factors influencing local recurrence. In particular, NAC and the status of the surgical margin were independent risk factors by multivariate analysis. The deep margin was resected at a close site in many NAC-treated patients, suggesting that NAC may lead to local recurrence and poor outcomes. No efficacy of NAC was observed, suggesting that the standard treatment of oral cancers is surgery alone. | |||||
書誌情報 |
International Journal of Oral and Maxillofacial Surgery 巻 41, 号 10, p. 1195-1200, 発行日 2012-10 |
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出版者 | ||||||
出版者 | International Association of Oral and Maxillofacial Surgeons | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09015027 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.ijom.2012.07.011 | |||||
権利 | ||||||
権利情報 | © 2012 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. | |||||
権利 | ||||||
権利情報 | NOTICE: this is the author’s version of a work that was accepted for publication in International Journal of Oral and Maxillofacial Surgery. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Journal of Oral and Maxillofacial Surgery, 41, 10(2012) | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | International Journal of Oral and Maxillofacial Surgery, 41(10), pp.1195-1200; 2012 |