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Markedly elevated serum testosterone, LH, and AMH levels were noted. Mild hirsutism and clitoromegaly were presented. Transabdominal ultrasonography and MRI revealed cystic mass occupied pelvic cavity probably originated from left ovary. Right ovary showed polycystic appearance. Laparoscopic left ovarian cystectomy was performed. After the surgery, her menstruation resumed along with normalized hormonal parameters, and clinical hyperandrogenism were improved. Since the scarcity of cellular lining of inner cyst wall, definitive pathological diagnosis was difficult. After the consultation with gynecological pathologist, the tumor was diagnosed as sex cord stromal tumor, highly suspicious for adult granulosa cell tumor. Residual left salpingo-oophorectomy was performed by additional laparoscopic surgery. Her serum testosterone and AMH levels were remained low with regular menstrual cycles and no evidence of recurrence. \nConclusions: Androgen-producing cystic granulosa cell tumor is rare gynecological disorders, which need both gynecologic oncological and endocrinological approach. 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The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1757-2215", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kitajima, Michio"}], "nameIdentifiers": [{"nameIdentifier": "124937", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kajimura, Itsuki"}], "nameIdentifiers": [{"nameIdentifier": "124938", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitajima, Yuriko"}], "nameIdentifiers": [{"nameIdentifier": "124939", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murakami, Naoko"}], "nameIdentifiers": [{"nameIdentifier": "124940", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumura, Asako"}], "nameIdentifiers": [{"nameIdentifier": "124941", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Kanako"}], "nameIdentifiers": [{"nameIdentifier": "124942", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Harada, Ayumi"}], "nameIdentifiers": [{"nameIdentifier": "124943", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hasegawa, Yuri"}], "nameIdentifiers": [{"nameIdentifier": "124944", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miura, Kiyonori"}], "nameIdentifiers": [{"nameIdentifier": "124945", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2023-03-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "JOR16_52.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "JOR16_52.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/28013/files/JOR16_52.pdf"}, "version_id": "548e41c9-cc50-4463-8dee-3b57616feb77"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Cystic granulosa cell tumor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Hyperandrogenism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "AMH", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "AMH producing purely cystic virilizing adult granulosa cell tumor in 17 years old girl: a case report and review of literatures", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "AMH producing purely cystic virilizing adult granulosa cell tumor in 17 years old girl: a case report and review of literatures"}]}, "item_type_id": "2", "owner": "6", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10069/00042144", "pubdate": {"attribute_name": "公開日", "attribute_value": "2023-03-28"}, "publish_date": "2023-03-28", "publish_status": "0", "recid": "28013", "relation": {}, "relation_version_is_last": true, "title": ["AMH producing purely cystic virilizing adult granulosa cell tumor in 17 years old girl: a case report and review of literatures"], "weko_shared_id": -1}
AMH producing purely cystic virilizing adult granulosa cell tumor in 17 years old girl: a case report and review of literatures
http://hdl.handle.net/10069/00042144
http://hdl.handle.net/10069/0004214473fbda73-8b48-4ecb-a97d-b5f9f0a284cc
名前 / ファイル | ライセンス | アクション |
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JOR16_52.pdf (1.3 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2023-03-28 | |||||
タイトル | ||||||
タイトル | AMH producing purely cystic virilizing adult granulosa cell tumor in 17 years old girl: a case report and review of literatures | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cystic granulosa cell tumor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hyperandrogenism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | AMH | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kitajima, Michio
× Kitajima, Michio× Kajimura, Itsuki× Kitajima, Yuriko× Murakami, Naoko× Matsumura, Asako× Matsumoto, Kanako× Harada, Ayumi× Hasegawa, Yuri× Miura, Kiyonori |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Androgen-producing granulosa cell tumor in adolescent girl is rare condition and clinical characteristics are not fully elucidated. Case presentation: Seventeen years old girl complained of secondary amenorrhea was referred to our out-patient consultation. Markedly elevated serum testosterone, LH, and AMH levels were noted. Mild hirsutism and clitoromegaly were presented. Transabdominal ultrasonography and MRI revealed cystic mass occupied pelvic cavity probably originated from left ovary. Right ovary showed polycystic appearance. Laparoscopic left ovarian cystectomy was performed. After the surgery, her menstruation resumed along with normalized hormonal parameters, and clinical hyperandrogenism were improved. Since the scarcity of cellular lining of inner cyst wall, definitive pathological diagnosis was difficult. After the consultation with gynecological pathologist, the tumor was diagnosed as sex cord stromal tumor, highly suspicious for adult granulosa cell tumor. Residual left salpingo-oophorectomy was performed by additional laparoscopic surgery. Her serum testosterone and AMH levels were remained low with regular menstrual cycles and no evidence of recurrence. Conclusions: Androgen-producing cystic granulosa cell tumor is rare gynecological disorders, which need both gynecologic oncological and endocrinological approach. Its clinical manifestations may bring some clues to the pathogenesis of ovulatory dysfunctions, such as polycystic ovary syndrome. |
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書誌情報 |
Journal of Ovarian Research 巻 16, 号 1, p. 52, 発行日 2023-03-15 |
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出版者 | ||||||
出版者 | BMC | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1757-2215 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/s13048-023-01134-0 | |||||
権利 | ||||||
権利情報 | © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of ovarian research, 16(1), art. no. 52; 2023 |