WEKO3
アイテム
{"_buckets": {"deposit": "d40aac8c-7c34-4adf-8e72-e3dee8443c83"}, "_deposit": {"created_by": 6, "id": "28016", "owners": [6], "pid": {"revision_id": 0, "type": "depid", "value": "28016"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00028016", "sets": ["11"]}, "author_link": ["124958", "124960", "124957", "124961", "124959"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2023-02-24", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageStart": "2146", "bibliographicVolumeNumber": "28", "bibliographic_titles": [{"bibliographic_title": "Molecules"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Quinones are frequently used as derivatization reagents in HPLC analysis to improve detection sensitivity. In the present study, a simple, sensitive, and selective chemiluminescence (CL) derivatization strategy for biogenic amines, prior to their HPLC-CL analysis, was developed. The novel CL derivatization strategy was established based on using anthraquinone-2-carbonyl chloride as derivatizing agent for amines and then using the unique property of the quinones’ moiety to generate reactive oxygen species (ROS) in response to UV irradiation. Typical amines such as tryptamine and phenethylamine were derivatized with anthraquinone-2-carbonyl chloride and then injected into an HPLC system equipped with an online photoreactor. The anthraquinone-tagged amines are separated and then UV-irradiated when they pass through a photoreactor to generate ROS from the quinone moiety of the derivative. Tryptamine and phenethylamine can be determined by measuring the chemiluminescence intensity produced by the reaction of the generated ROS with luminol. The chemiluminescence disappears when the photoreactor is turned off, suggesting that ROS are no longer generated from the quinone moiety in the absence of UV irradiation. This result indicates that the generation of ROS could be controlled by turning the photoreactor on and off. Under the optimized conditions, the limits of detection for tryptamine and phenethylamine were 124 and 84 nM, respectively. The developed method is successfully applied to determine the concentrations of tryptamine and phenethylamine in wine samples.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Molecules, 28(5), art. no. 2146; 2023", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "MDPI"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3390/molecules28052146", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1420-3049", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kishikawa, Naoya"}], "nameIdentifiers": [{"nameIdentifier": "124957", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "El-Maghrabey, Mahmoud"}], "nameIdentifiers": [{"nameIdentifier": "124958", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawamoto, Ayaka"}], "nameIdentifiers": [{"nameIdentifier": "124959", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohyama, Kaname"}], "nameIdentifiers": [{"nameIdentifier": "124960", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kuroda, Naotaka"}], "nameIdentifiers": [{"nameIdentifier": "124961", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2023-03-28"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "M28_2146.pdf", "filesize": [{"value": "1.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1400000.0, "url": {"label": "M28_2146.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/28016/files/M28_2146.pdf"}, "version_id": "8250a1cd-3536-4a5d-a0ac-ce885ab688f7"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "chemiluminescence", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anthraquinone", "subitem_subject_scheme": "Other"}, {"subitem_subject": "derivatization", "subitem_subject_scheme": "Other"}, {"subitem_subject": "UV irradiation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "amine", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Determination of Anthraquinone-Tagged Amines Using High-Performance Liquid Chromatography with Online UV Irradiation and Luminol Chemiluminescence Detection", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Determination of Anthraquinone-Tagged Amines Using High-Performance Liquid Chromatography with Online UV Irradiation and Luminol Chemiluminescence Detection"}]}, "item_type_id": "2", "owner": "6", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10069/00042147", "pubdate": {"attribute_name": "公開日", "attribute_value": "2023-03-28"}, "publish_date": "2023-03-28", "publish_status": "0", "recid": "28016", "relation": {}, "relation_version_is_last": true, "title": ["Determination of Anthraquinone-Tagged Amines Using High-Performance Liquid Chromatography with Online UV Irradiation and Luminol Chemiluminescence Detection"], "weko_shared_id": -1}
Determination of Anthraquinone-Tagged Amines Using High-Performance Liquid Chromatography with Online UV Irradiation and Luminol Chemiluminescence Detection
http://hdl.handle.net/10069/00042147
http://hdl.handle.net/10069/0004214786cb968d-643a-46f6-8e72-59275a50c651
名前 / ファイル | ライセンス | アクション |
---|---|---|
M28_2146.pdf (1.4 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2023-03-28 | |||||
タイトル | ||||||
タイトル | Determination of Anthraquinone-Tagged Amines Using High-Performance Liquid Chromatography with Online UV Irradiation and Luminol Chemiluminescence Detection | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chemiluminescence | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | anthraquinone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | derivatization | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | UV irradiation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | amine | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kishikawa, Naoya
× Kishikawa, Naoya× El-Maghrabey, Mahmoud× Kawamoto, Ayaka× Ohyama, Kaname× Kuroda, Naotaka |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Quinones are frequently used as derivatization reagents in HPLC analysis to improve detection sensitivity. In the present study, a simple, sensitive, and selective chemiluminescence (CL) derivatization strategy for biogenic amines, prior to their HPLC-CL analysis, was developed. The novel CL derivatization strategy was established based on using anthraquinone-2-carbonyl chloride as derivatizing agent for amines and then using the unique property of the quinones’ moiety to generate reactive oxygen species (ROS) in response to UV irradiation. Typical amines such as tryptamine and phenethylamine were derivatized with anthraquinone-2-carbonyl chloride and then injected into an HPLC system equipped with an online photoreactor. The anthraquinone-tagged amines are separated and then UV-irradiated when they pass through a photoreactor to generate ROS from the quinone moiety of the derivative. Tryptamine and phenethylamine can be determined by measuring the chemiluminescence intensity produced by the reaction of the generated ROS with luminol. The chemiluminescence disappears when the photoreactor is turned off, suggesting that ROS are no longer generated from the quinone moiety in the absence of UV irradiation. This result indicates that the generation of ROS could be controlled by turning the photoreactor on and off. Under the optimized conditions, the limits of detection for tryptamine and phenethylamine were 124 and 84 nM, respectively. The developed method is successfully applied to determine the concentrations of tryptamine and phenethylamine in wine samples. | |||||
書誌情報 |
Molecules 巻 28, 号 5, p. 2146, 発行日 2023-02-24 |
|||||
出版者 | ||||||
出版者 | MDPI | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1420-3049 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/molecules28052146 | |||||
権利 | ||||||
権利情報 | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Molecules, 28(5), art. no. 2146; 2023 |