A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspiration showing a remarkable reduction of erythroblasts. Finally, cyclosporine A successfully improved PRCA. Although both SLE and MG have the potential complication of PRCA, we report here a case of isoniazid-triggered PRCA.
雑誌名
Rheumatology International
巻
30
号
12
ページ
1643 - 1645
発行年
2010-11
出版者
Springer Berlin
ISSN
01728172
EISSN
1437160X
書誌レコードID
AA0040456X
PubMed番号
19705120
DOI
10.1007/s00296-009-1113-2
権利
c 2009 Springer-Verlag.
The original publication is available at www.springerlink.com
Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis.
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