@phdthesis{oai:nagasaki-u.repo.nii.ac.jp:00001051,
 author = {田中, 健一朗},
 month = {Mar},
 note = {Objective: The early detection and treatment of COPD requires comprehensive follow-up over a long period. The aim of this study was to determine the effects of a comprehensive long-term intervention system developed by the COPD Task Force for a rural city in Japan during a 7-year period. Methods: This prospective, community-based longitudinal study encompassed 2006-2013 in Matsuura City, Japan. Primary and secondary screenings were performed for the early diagnosis and treatment of COPD. Individuals diagnosed with COPD were managed by the COPD Task Force's comprehensive early intervention system. The outcomes of interest were the rate of continuous follow-up after the diagnosis of COPD, the smoking cessation rate, and changes in the pulmonary function during a 7-year period. Subjects: The study included 8,878 residents of 50-89 years of age who resided in Matsuura in 2006. Results: In total, 140 participants received definitive diagnoses of COPD in 2006. After 7 years of intervention, 34 patients withdrew; 78 (74%) patients continued with treatment in our intervention system. The rate of smoking cessation was significantly increased in the intervention group (from 30% to 68%; p<0.01) over the 7-year period. The change in forced expiratory volume in 1 second (FEV1) was -23.2 mL/year. Conclusion: Our systematic longitudinal intervention system during a 7-year period led to high rates of follow-up and smoking cessation. Furthermore, our system may be able to prevent the decline of FEV1 in COPD patients. This intervention system may be effective in rural cities with few respiratory physicians., 長崎大学学位論文 学位記番号:博(医歯薬)甲第1023号 学位授与年月日:平成30年3月7日, Author: Kenichiro Tanaka, Hideaki Senjyu, Yuichi Tawara, Takako Tanaka, Masaharu Asai, Mitsuru Tabusadani, Sumihisa Honda, Terumitsu Sawai, Ryo Kozu, Citation: Internal Medicine, 57(16), pp.2315-2323; 2018, Nagasaki University (長崎大学), 博士(医学) (2018-03-07)},
 school = {Nagasaki University (長崎大学)},
 title = {Effects of Systematic Intervention for Chronic Obstructive Pulmonary Disease on Follow-up and Smoking Cessation Rates and Changes of the Pulmonary Function: A 7-year Longitudinal Study in a Japanese Rural City},
 year = {2018}
}