{"created":"2023-05-15T16:38:46.708218+00:00","id":12495,"links":{},"metadata":{"_buckets":{"deposit":"faf2b098-2b76-4872-aa92-13f3dd4ff905"},"_deposit":{"created_by":2,"id":"12495","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"12495"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00012495","sets":["8:9"]},"author_link":["46308","46315","46304","46310","46302","46296","46317","46311","46305","46316","46318","46313","46294","46301","46319","46309","46297","46299","46312","46314","46295","46300","46306","46298","46303","46307"],"item_2_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Annual changes in susceptibility of clinical isolates to biapenem"}]},"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"351","bibliographicPageStart":"329","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"日本化学療法学会雑誌"},{"bibliographic_title":"Japanese Journal of Chemotherapy","bibliographic_titleLang":"en"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Staphylococcus aureus，Streptococcus pneumoniae，Escherichia coli，Pseudomonas aeruginosaを含む14 菌種，計1,032 株の新規カルバペネム系薬であるbiapenem（BIPM）に対する年次別薬剤感受性の推移について寒天平板希釈法を用いて検討した。菌株は1994 年1 月から1996 年12 月の間に長崎大学医学部附属病院の患者より分離された株を用いた。MIC50，MIC90 値により比較したところ，メチシリン耐性菌を含むS. aureus，ペニシリン耐性菌を含むS. pneumoniae，Streptococcus pyogenes，Enterococcus faecalis，E. coli，Klebsiella pneumoniae，Enterobacter cloacae，Proteus mirabilis，Acinetobacter baumannii およびMoraxella catarrhalis には薬剤耐性化傾向は認められなかった。しかし，Staphylococcus epidermidis およびSerratia marcescens ではMIC50 値でみたところ，カルバペネム系薬に対し，わずかに耐性菌の増加傾向がみられた。また，緑膿菌にもMIC90 値でみる限り，カルバペネム系薬に耐性を示す株の増加傾向がみられたものの，BIPM に対する耐性化傾向は他のカルバペネム系薬より軽度であった。1996 年に分離されたHaemophilus influenzae にカルバペネムを含むβ.ラクタム耐性株が認められたため，今後の動向に注意が必要と思われる。","subitem_description_type":"Abstract"},{"subitem_description":"Annual changes in susceptibility of biapenem（BIPM），a new injectable carbapenem，against 1,032 clinical strains（14 species）including Staphylococcus aureus，Streptococcus pneumoniae，Escherichia coli， Pseudomonas aeruginosa，etc., were determined by agar dilution．Strains were isolated from patients in the Nagasaki University Hospital from January 1994 to December 1996．Comparison of annual changes of MIC50 and MIC90 against S. aureus including methicillin.resistant strains，S. pneumoniae including penicillin.resistant strains，Streptococcus pyogenes，Enterococcus faecalis，E. coli，Klebsiella pneumoniae， Enterobacter cloacae，Proteus mirabilis，Acinetobacter baumannii，and Moraxella catarrhalis did not show increased resistance．Staphylococcus epidermidis and Serratia marcescens showed a slight increase in carbapenem.resistant strains，judging from MIC50．Although P. aeruginosa also showed an increase in carbapenem.resistant strains by the comparison of MIC90，the tendency toward BIPM resistance against this species was lower than those of other carbapenems. Among Haemophilus influenzae isolated in 1996， some strains were resistant strains toβ.lactams including carbapenems，so we must note this tendency．","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"日本化学療法学会雑誌, 50(6), pp.329-351; 2002","subitem_description_type":"Other"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"46307","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hirakata, Yoichi"}]},{"nameIdentifiers":[{"nameIdentifier":"46308","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Matsuda, Junichi"}]},{"nameIdentifiers":[{"nameIdentifier":"46309","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Mochida, Chikako"}]},{"nameIdentifiers":[{"nameIdentifier":"46310","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakano, Michiko"}]},{"nameIdentifiers":[{"nameIdentifier":"46311","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hirayama, Mitsukuni"}]},{"nameIdentifiers":[{"nameIdentifier":"46312","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Iori, Fumiaki"}]},{"nameIdentifiers":[{"nameIdentifier":"46313","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kamihira, Shimeru"}]},{"nameIdentifiers":[{"nameIdentifier":"46314","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tomono, Kazunori"}]},{"nameIdentifiers":[{"nameIdentifier":"46315","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yanagihara, Katsunori"}]},{"nameIdentifiers":[{"nameIdentifier":"46316","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Miyazaki, Yoshitugu"}]},{"nameIdentifiers":[{"nameIdentifier":"46317","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kadota, Junichi"}]},{"nameIdentifiers":[{"nameIdentifier":"46318","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hara, Kohei"}]},{"nameIdentifiers":[{"nameIdentifier":"46319","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kohno, Shigeru"}]}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本化学療法学会"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10472127","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13407007","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Japanese Society of Chemotherapy"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"平泻, 洋一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松田, 淳一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"餅田, 親子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中野, 路子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"平山, 三国"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊折, 文秋"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"上平, 憲"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"朝野, 和典"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"壼原, 克典"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宮崎, 義継"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"門田, 淳一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"原, 耕平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"河野, 茂"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-22"}],"displaytype":"detail","filename":"JJC50_329.pdf","filesize":[{"value":"266.4 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に対する各種臨床分離菌株の薬剤感受性の年次推移について"}]},"item_type_id":"2","owner":"2","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-12-05"},"publish_date":"2011-12-05","publish_status":"0","recid":"12495","relation_version_is_last":true,"title":["Biapenem に対する各種臨床分離菌株の薬剤感受性の年次推移について"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T00:53:19.391425+00:00"}