@article{oai:nagasaki-u.repo.nii.ac.jp:00001280,
 author = {Yamanashi, Hirotomo and Kulkarni, Bharati and Edwards, Tansy and Kinra, Sanjay and Koyamatsu, Jun and Nagayoshi, Mako and Shimizu, Yuji and Maeda, Takahiro and Cox, Sharon E},
 issue = {7},
 journal = {Geriatrics & Gerontology International},
 month = {Jul},
 note = {Aim: Although several risk factors contribute to the development of sarcopenia, whether preclinical atherosclerosis contributes to the risk of sarcopenia is not established. The present cross-sectional study aimed to investigate if there is an association between preclinical atherosclerosis and muscle strength among two ethnic populations. Methods: Participants included individuals aged ?40 years and enrolled in the third follow-up examination of the Andhra Pradesh Children and Parents Study, India, and in the baseline assessments of the Nagasaki Islands Study, Japan. Preclinical atherosclerosis was evaluated by carotid intima-media thickness, brachial-ankle pulse wave velocity, cardio-ankle vascular index. The association of carotid intima-media thickness and pulse wave velocity/cardio-ankle vascular index with handgrip strength (HGS) was analyzed separately in the sexes and for hypertensive status from the two cohorts using a multivariable linear regression model. Results: Data on a total of 1501 participants in India and 3136 participants in Japan were analyzed. Carotid intima-media thickness was negatively associated with HGS in non-hypertensive Indian men (B coefficient = ?5.38, P = 0.036). Arterial stiffness was also associated with HGS in non-hypertensive Indian men (B = ?0.97, P = 0.001), but not in hypertensive Indian men. Same as Indian men, we found the significant associations between arterial stiffness and HGS in non-hypertensive women in both India and Japan (B = ?0.44, P = 0.020, B = ?0.63, P = 0.016, respectively), but not in hypertensive women. Conclusions: The negative association between preclinical atherosclerosis and HGS was dominantly found in non-hypertensive participants., Geriatrics and Gerontology International, 18(7), pp.1071-1078; 2018},
 pages = {1071--1078},
 title = {Association between atherosclerosis and handgrip strength in non-hypertensive populations in India and Japan},
 volume = {18},
 year = {2018}
}