{"created":"2023-05-15T16:39:28.750574+00:00","id":13391,"links":{},"metadata":{"_buckets":{"deposit":"0c5e5cb5-8cc5-4909-8bd0-c1cabed1dcd2"},"_deposit":{"created_by":2,"id":"13391","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"13391"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00013391","sets":["8:9"]},"author_link":["48382","48373","48380","48374","48375","48376","48379","48378","48372","48377","48381"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"430","bibliographicPageStart":"420","bibliographicVolumeNumber":"81","bibliographic_titles":[{"bibliographic_title":"Respiration; international review of thoracic diseases"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibrosis and a poor prognosis. Alveolar epithelial cells (AECs) are considered to play important roles by releasing growth factors and matrix metalloproteinases (MMPs) and by being involved in epithelial mesenchymal transition in IPF. Doxycycline hydrochloride (DOXY), an inhibitor of MMPs, attenuates pulmonary fibrosis in models and in patients with IPF; however, the mechanism of this action remains obscure.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Respiration, 81(5), pp.420-430; 2011","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Karger AG,"}]},"item_2_relation_11":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"21502778","subitem_relation_type_select":"PMID"}}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1159/000324080","subitem_relation_type_select":"DOI"}}]},"item_2_relation_42":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://hdl.handle.net/10069/26718"}]}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2011 S. Karger AG, Basel"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00816840","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00257931","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"14230356","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fujita, Hanako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakamoto, Noriho"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishimatsu, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kakugawa, Tomoyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hara, Shintaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hara, Atsuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Amenomori, Misato"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishimoto, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagata, Towako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mukae, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohno, Shigeru"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-22"}],"displaytype":"detail","filename":"Res81_420.pdf","filesize":[{"value":"1.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Res81_420.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/13391/files/Res81_420.pdf"},"version_id":"46182be5-4071-4281-b174-b82643ba7f75"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Alveolar epithelial cells","subitem_subject_scheme":"Other"},{"subitem_subject":"Connective tissue growth factor","subitem_subject_scheme":"Other"},{"subitem_subject":"Epithelial mesenchymal transition","subitem_subject_scheme":"Other"},{"subitem_subject":"Fibroblast","subitem_subject_scheme":"Other"},{"subitem_subject":"Smad","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of doxycycline on production of growth factors and matrix metalloproteinases in pulmonary fibrosis.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of doxycycline on production of growth factors and matrix metalloproteinases in pulmonary fibrosis."}]},"item_type_id":"2","owner":"2","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-08-02"},"publish_date":"2011-08-02","publish_status":"0","recid":"13391","relation_version_is_last":true,"title":["Effects of doxycycline on production of growth factors and matrix metalloproteinases in pulmonary fibrosis."],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T00:38:50.837225+00:00"}