{"created":"2023-05-15T16:39:29.615564+00:00","id":13406,"links":{},"metadata":{"_buckets":{"deposit":"719361db-56f6-48be-9a7e-9f2001b2ff08"},"_deposit":{"created_by":2,"id":"13406","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"13406"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00013406","sets":["29:30"]},"author_link":["48451","48449","48452","48448","48455","48450","48453","48454"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"1032","bibliographicPageStart":"1029","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Internal Medicine"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report a 36-year-old woman presenting with hypertensive encephalopathy followed by bulbar palsy and quadriplegia. After an extensive screening for secondary causes of hypertension, the patient was suspected of having pheochromocytoma due to increased levels of catecholamines in the plasma and the urine, and positive 131I-metaiodobenzylguanidine (MIBG) accumulation in the gallbladder. However, MIBG accumulation was not reproducible without any tumors accompanying this accumulation in the gallbladder. A diagnosis of acute intermittent porphyria was finally confirmed based on the characteristic pictures, increased urinary excretion of porphobilinogen, and identification of a heterozygous missense mutation of R173W in the hydroxymethylbilane synthase gene. This case highlights a pitfall in utilizing MIBG to detect a source of excessive catecholamine and also suggests the importance of having a complete clinical history and extensive work-up of any possible differential diagnosis. We also review the potential mechanism by which falsepositive MIBG accumulation occurs.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Internal Medicine, 50(9), pp.1029-1032; 2011","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japanese Society of Internal Medicine"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2169/internalmedicine.50.5096","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2011 by The Japanese Society of Internal Medicine"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10827774","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09182918","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"日本内科学会"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Masuda, Tomoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ota, Rie"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ando, Takao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Naoto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Horie, Yutaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshimura, Toshiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Motomura, Masakatsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawakami, Atsushi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-22"}],"displaytype":"detail","filename":"IntMed50_1029.pdf","filesize":[{"value":"702.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IntMed50_1029.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/13406/files/IntMed50_1029.pdf"},"version_id":"9a292443-f764-4cd5-883c-2cec2703f314"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Acute intermittent porphyria","subitem_subject_scheme":"Other"},{"subitem_subject":"False-positive","subitem_subject_scheme":"Other"},{"subitem_subject":"MIBG","subitem_subject_scheme":"Other"},{"subitem_subject":"Pheochromocytoma","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"False-Positive Accumulation of Metaiodobenzylguanidine in a Case with Acute Intermittent Porphyria","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"False-Positive Accumulation of Metaiodobenzylguanidine in a Case with Acute Intermittent Porphyria"}]},"item_type_id":"2","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-08-04"},"publish_date":"2011-08-04","publish_status":"0","recid":"13406","relation_version_is_last":true,"title":["False-Positive Accumulation of Metaiodobenzylguanidine in a Case with Acute Intermittent Porphyria"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-05-15T18:53:04.385177+00:00"}