@article{oai:nagasaki-u.repo.nii.ac.jp:00014071,
 author = {Moritaka, Kentaro and Zeredo, Jorge L. and Kimoto, Mari and Nasution, Fajar H. and Hirano, Takafumi and Toda, Kazuo},
 issue = {5},
 journal = {The American Journal of Chinese Medicine},
 month = {},
 note = {A descending inhibitory mechanism from the periaqueductal gray (PAG) to the spinal cord through the nucleus raphe magnus (NRM) is strongly involved in endogenous analgesic system produced by acupuncture stimulation. In addition to the PAG to NRM system which descends in the medial pathway of the brain stem, the nucleus reticularis lateralis (NRL) situated in the lateral part of the brain stem is reported to play an important role in modulating centrifugal antinociceptive action. In the present study, to clarify the role of NRL in acupuncture analgesia, we investigated the response properties of NRL neurons to acupuncture stimulation. The majority of NRM-projecting NRL neurons were inhibited by electroacupuncture stimulation. This effect was antagonized by ionophoretic application of naloxone, indicating that endogenous opioids act directly onto these NRL neurons. By contrast, about half of spinal projecting NRL neurons were excited by electroacupuncture stimulation, suggesting that part of the NRL neurons may modulate pain transmission directly at the spinal level., The American Journal of Chinese Medicine, 38(5), pp.869-880; 2010},
 pages = {869--880},
 title = {Response Properties of Nucleus Reticularis Lateralis Neurons After Electroacupuncture Stimulation in Rats},
 volume = {38},
 year = {2010}
}