@article{oai:nagasaki-u.repo.nii.ac.jp:00001422, author = {Fujita, Yuya and Fukui, Shoichi and Ishida, Midori and Endo, Yushiro and Tsuji, Sosuke and Takatani, Ayuko and Igawa, Takashi and Shimizu, Toshimasa and Umeda, Masataka and Sumiyoshi, Remi and Nishino, Ayako and Koga, Tomohiro and Kawashiri, Shin-ya and Iwamoto, Naoki and Ichinose, Kunihiro and Tamai, Mami and Nakamura, Hideki and Origuchi, Tomoki and Kawakami, Atsushi}, issue = {20}, journal = {Internal Medicine, The Japanese Society of Internal Medicine}, month = {Oct}, note = {A 70-year-old Japanese woman presented to our hospital with gait disturbance and cognitive dysfunction. Since she had arthritis, lymphopenia, hypocomplementemia, and anti-nuclear and anti-double-stranded DNA antibodies, she was diagnosed with systemic lupus erythematosus (SLE). T2-weighted magnetic resonance imaging revealed bilateral hyperintensities in the putamen. Based on her cognitive impairment, muscle rigidity, and high levels of interleukin-6 in the cerebrospinal fluid, we believed she had developed a complication of a neuropsychiatric disease and administered corticosteroids and intravenous cyclophosphamide therapy. Her cognitive function fully recovered, and her gait disturbance improved. Attending to cognitive impairment in elderly SLE patients is necessary., Internal medicine, 57(20), pp.3025-3028; 2018}, pages = {3025--3028}, title = {Reversible Cognitive Dysfunction in Elderly-onset Systemic Lupus Erythematosus, Successfully Treated with Aggressive Immunosuppressive Therapy}, volume = {57}, year = {2018} }