{"created":"2023-05-15T16:40:19.786344+00:00","id":14546,"links":{},"metadata":{"_buckets":{"deposit":"1e2fc10a-8d5e-4a75-a40c-df6cb8d946cb"},"_deposit":{"created_by":2,"id":"14546","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"14546"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00014546","sets":["35:36"]},"author_link":["53404","53402","53405","53403","53401","53400"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"396","bibliographicPageStart":"391","bibliographicVolumeNumber":"72","bibliographic_titles":[{"bibliographic_title":"Journal of Veterinary Medical Science"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Tick-borne encephalitis virus (TBEV) is a zoonotic agent that causes acute central nervous system (CNS) disease in humans. In this study, we examined the pathogenic process following intracerebral infection with the Oshima strain of TBEV in a mouse model. Intracerebral infection resulted in dose-dependent mortality, and all mice died following challenge with 102 PFU or more of the virus within 10 days. Acutely necrotic neurons and widespread inflammation were observed throughout the CNS. We therefore conclude that mortality following intracerebral infection results from a direct CNS pathology.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Journal of Veterinary Medical Science, 72(4), pp.391-396; 2010","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Society of Veterinary Science"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1292/jvms.09-0258","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright(c) 2010 by the Japanese Society of Veterinary Science"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10796138","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09167250","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13477439","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"日本獣医学会"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayasaka, Daisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagata, Noriyo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hasegawa, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sata, Tetsutaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takashima, Ikuo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koike, Satoshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-22"}],"displaytype":"detail","filename":"JVMS72_391.pdf","filesize":[{"value":"695.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JVMS72_391.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/14546/files/JVMS72_391.pdf"},"version_id":"7b6a5c49-9913-4a34-9dd3-33e118db5dec"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Central nervous system","subitem_subject_scheme":"Other"},{"subitem_subject":"Mouse","subitem_subject_scheme":"Other"},{"subitem_subject":"Pathogenesis","subitem_subject_scheme":"Other"},{"subitem_subject":"Tick-borne disease","subitem_subject_scheme":"Other"},{"subitem_subject":"Virus infection","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model"}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-12-21"},"publish_date":"2010-12-21","publish_status":"0","recid":"14546","relation_version_is_last":true,"title":["Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-05-15T18:54:46.212892+00:00"}