{"created":"2023-05-15T16:40:20.177888+00:00","id":14555,"links":{},"metadata":{"_buckets":{"deposit":"2fefa059-36d1-48b3-9ab3-cf1d36b66671"},"_deposit":{"created_by":2,"id":"14555","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"14555"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00014555","sets":["8:9"]},"author_link":["53463","53473","53471","53472","53470","53468","53474","53465","53464","53466","53469","53467"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"101","bibliographicPageEnd":"697","bibliographicPageStart":"694","bibliographicVolumeNumber":"57","bibliographic_titles":[{"bibliographic_title":"Hepato-Gastroenterology"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background/Aims: Pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (1CTP) is a sensitive serum marker for metastatic bone carcinomas and may also be associated with invasiveness of various carcinomas. To clarify the significance of 1CTP in hepato-biliary pancreas malignancies, we examined the relationship between clinicopathological features and serum level of 1CTP. Methodology: The subjects were 75 patients who underwent surgical resections including 27 patients with liver carcinomas, 15 with extra-hepatic biliary carcinomas, 14 pancreatic carcinomas and 19 benign diseases. Results: 1CTP level tended to be higher in the malignant diseases than in benign diseases but this difference was not significant (p=0.065). Compared to benign adenoma, 1CTP level in the malignant diseases was significantly higher (p=0.049). 1CTP level tended to be higher in patients with cholangitis compared to those with no inflammation or benign tumors (p=0.065). 1CTP was not correlated with any tumor markers. 1CTP was not associated with node status and vascular infiltrations. 1CTP level tended to be lower in patients with poor differentiation. Conclusions: Serum level of 1CTP might be a predictive marker for hepatobiliary pancreas malignancies but also reflects the degree of co-existing cholangitis.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Hepato-Gastroenterology, 57(101), pp.694-697; 2010","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Thieme"}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© H.G.E. Update Medical Publishing S.A."}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00213244","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"01726390","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nanashima, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeshita, Hiroaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tobinaga, Syuuichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Araki, Masato"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sumida, Yorihisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kunizaki, Masaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Kenji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abo, Takafumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hidaka, Shigekazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sawai, Terumitsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yasutake, Toru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagayasu, Takeshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-22"}],"displaytype":"detail","filename":"HepGas57_694.pdf","filesize":[{"value":"221.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HepGas57_694.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/14555/files/HepGas57_694.pdf"},"version_id":"34d10de8-daab-48d8-8af6-f2babc0de794"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"1CTP","subitem_subject_scheme":"Other"},{"subitem_subject":"Cholangitis","subitem_subject_scheme":"Other"},{"subitem_subject":"Hepatobiliary pancreas","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Measurement of serum marker for bone metastasis (1-CTP) in hepatobiliary and pancreas malignancies","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Measurement of serum marker for bone metastasis (1-CTP) in hepatobiliary and pancreas malignancies"}]},"item_type_id":"2","owner":"2","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-08-01"},"publish_date":"2011-08-01","publish_status":"0","recid":"14555","relation_version_is_last":true,"title":["Measurement of serum marker for bone metastasis (1-CTP) in hepatobiliary and pancreas malignancies"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T00:17:34.432167+00:00"}