@article{oai:nagasaki-u.repo.nii.ac.jp:00014560,
 author = {Miyazaki, Takuro and Sakai, Tetsuya and Tsuchiya, Tomoshi and Yamasaki, Naoya and Tagawa, Tsutomu and Mine, Mariko and Shibata, Yoshisada and Nagayasu, Takeshi},
 issue = {6},
 journal = {European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
 month = {Jun},
 note = {Objective: Chronic pain is a common complication after thoracic surgery. The most important factor appears to be intercostal nerve damage. The purpose of this prospective study was to objectively evaluate intercostal nerve damage associated with post-thoracotomy pain after three surgical procedures using current perception threshold testing. Methods: The 32 patients were classified into three groups: the video-assisted thoracic surgery group (n=7), the video-assisted minithoracotomy with metal retractors group (n=15), and the conventional thoracotomy group (n=10). Intercostal nerve function was assessed by a series of 2000-Hz (Aβ fiber), 250-Hz (Aδ fiber), and 5-Hz (C fiber) stimuli using current perception threshold testing (Neurometer CPT/C(®)). The current perception threshold values were measured before and 1, 2, 4, 12, and 24 weeks after surgery. The intensities of ongoing pain were also assessed using a numeric rating scale (0-10). Results: The video-assisted thoracic surgery group showed no changes in any current perception threshold values and no residual pain more than 12 weeks after surgery. The video-assisted minithoracotomy with metal retractors group and the conventional thoracotomy group showed significantly higher current perception threshold values at 2000Hz 1 week after surgery (p=0.0013, p=0.0012, respectively), with pain in approximately 70% of patients 12 weeks after surgery. The correlation between current perception threshold values at 2000Hz and the intensities of ongoing pain 4 and 12 weeks after surgery was significant (p=0.03, p=0.04, respectively). Conclusions: This is the first study that objectively evaluated pain after video-assisted thoracic surgery. The results suggest that the Aβ and Aδ fibers play a significant role in the development of intercostal nerve damage. The current perception threshold values clearly demonstrated that video-assisted thoracic surgery is a less-invasive procedure resulting in less post-thoracotomy pain and, they have some possibilities to objectively evaluate the ongoing pain after surgery., European journal of cardio-thoracic surgery, 39(6), pp.1033-1039; 2011},
 pages = {1033--1039},
 title = {Assessment and follow-up of intercostal nerve damage after video-assisted thoracic surgery.},
 volume = {39},
 year = {2011}
}