@article{oai:nagasaki-u.repo.nii.ac.jp:00014600,
 author = {Yamanouchi, Kosho and Takatsuki, Mitsuhisa and Hidaka, Masaaki and Soyama, Akihiko and Kanematsu, Takashi and Eguchi, Susumu},
 issue = {3},
 journal = {Journal of hepato-biliary-pancreatic sciences},
 month = {May},
 note = {BACKGROUND/PURPOSE: Early identification and treatment of fungal infections is essential for recipients of liver transplants, but the sensitivity of surveillance culture is insufficient. Measurement of the serum level of β-D: -glucan is a rapid diagnostic strategy for invasive fungal infection. We aimed to evaluate the significance of serum β-D: -glucan levels in transplant recipients after living donor liver transplantation (LDLT). METHODS: We retrospectively analyzed the clinical and laboratory data of 100 consecutive adult transplant recipients after LDLT performed between August 1997 and August 2009. RESULTS: Seventy-one had high serum β-D: -glucan levels (>20 pg/ml) after LDLT. Nearly half (47.2%) of the episodes of increase occurred within the first 5 days after surgery. The mortality rate of the recipients with high serum β-D: -glucan levels was similar to that of the recipients without high levels. However, in terms of the time line of increase, the recipients with high serum β-D: -glucan levels from 15 days onward after surgery showed a significantly higher mortality rate than those with high levels before 15 days after surgery (33.3 and 4.3%, respectively; p < 0.001). CONCLUSIONS: High serum levels of β-D: -glucan at late time points after LDLT indicate established fungal infection and higher mortality., Journal of hepato-biliary-pancreatic sciences, 18(3), pp.432-435; 2011},
 pages = {432--435},
 title = {Significance of serum β-d-glucan levels in recipients of living donor liver transplantation},
 volume = {18},
 year = {2011}
}