@phdthesis{oai:nagasaki-u.repo.nii.ac.jp:00001487,
 author = {佐賀里, 昭},
 month = {Mar},
 note = {Introduction: Studies of cerebral hemodynamics during motor learning have mostly focused on neurorehabilitation interventions and their effectiveness. However, only a few imaging studies of motor learning and the underlying complex cognitive processes have been performed. Methods: We measured cerebral hemodynamics using near-infrared spectroscopy (NIRS) in relation to acquisition patterns of motor skills in healthy subjects using character entry into a touch-screen terminal. Twenty healthy, right-handed subjects who had no previous experience with character entry using a touch-screen terminal participated in this study. They were asked to enter the characters of a randomly formed Japanese syllabary into the touch-screen terminal. All subjects performed the task with their right thumb for 15 s alternating with 25 s of rest for 30 repetitions. Performance was calculated by subtracting the number of incorrect answers from the number of correct answers, and gains in motor skills were evaluated according to the changes in performance across cycles. Behavioral and oxygenated hemoglobin concentration changes across task cycles were analyzed using Spearman’s rank correlations. 
Results: Performance correlated positively with task cycle, thus confirming motor learning. Hemodynamic activation over the left sensorimotor cortex (SMC) showed a positive correlation with task cycle, whereas activations over the right prefrontal cortex (PFC) and supplementary motor area (SMA) showed negative correlations. Conclusions: 
We suggest that increases in finger momentum with motor learning are reflected in the activity of the left SMC. We further speculate that the right PFC and SMA were activated during the early phases of motor learning, and that this activity was attenuated with learning progress., 長崎大学学位論文 学位記番号:博(医歯薬)甲第857号 学位授与年月日:平成28年3月18日, Author: Akira Sagari, Naoki Iso, Takefumi Moriuchi, Kakuya Ogahara, Eiji Kitajima, Koji Tanaka, Takayuki Tabira, Toshio Higashi, Citation: PLOS ONE, 10(10), e0140552; 2015, Nagasaki University (長崎大学), 博士(医学) (2016-03-18)},
 school = {Nagasaki University (長崎大学)},
 title = {Changes in Cerebral Hemodynamics during Complex Motor Learning by Character Entry into Touch-Screen Terminals},
 year = {2016}
}