@article{oai:nagasaki-u.repo.nii.ac.jp:00001494, author = {Ito, Hiromu and Yamamoto, Taro and Morita, Satoru}, journal = {Applied Mathematics and Computation}, month = {May}, note = {Sexually transmitted infections (STIs) are an ongoing public health concern. Despite many efforts, STIs have not been eradicated. Most STIs are infected through “horizontal” sexual contact and “vertical” mother-to-child transmission. We therefore need to explore the mathematical relationship between horizontal and vertical transmissions, which is necessary for the strategic eradication of STIs. Here, we constructed a simple model to demonstrate the infection dynamics of STIs with vertical transmission. We proposed a new formulation of the basic reproduction number (R0) for STIs over generations, and showed that vertical transmission exerts a smaller effect on the R0 than horizontal transmission. We also performed agent-based simulations to validate our theoretical predictions., Applied Mathematics and Computation, 348, pp.363-370; 2019}, pages = {363--370}, title = {Demography of sexually transmitted infections with vertical transmission}, volume = {348}, year = {2019} }