{"created":"2023-05-15T16:40:48.896222+00:00","id":15224,"links":{},"metadata":{"_buckets":{"deposit":"71299920-e4dd-430c-8130-a7c56a22d5c6"},"_deposit":{"created_by":2,"id":"15224","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"15224"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00015224","sets":["10:11"]},"author_link":["56065","56062","56067","56063","56068","56059","56061","56066","56064","56060"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"336","bibliographicPageStart":"332","bibliographicVolumeNumber":"162","bibliographic_titles":[{"bibliographic_title":"The British journal of dermatology"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Summary Background Previous studies suggest that CCL13 may have some role in the pathogenesis of systemic sclerosis (SSc). Objectives To determine serum levels of CCL13 and its clinical associations in patients with SSc. Methods Serum CCL13 levels were examined by enzyme-linked immunosorbent assay in 80 patients with SSc, 20 patients with systemic lupus erythematosus (SLE), 20 patients with dermatomyositis (DM), 29 patients with atopic dermatitis (AD) and 50 healthy individuals. Results Mean +/- SD serum CCL13 levels were elevated in patients with SSc (81.3 +/- 55.8 pg mL(-1)) compared with healthy controls (15.0 +/- 9.9 pg mL(-1); P < 0.001) and patients with SLE (22.0 +/- 6.9 pg mL(-1); P < 0.001), DM (24.4 +/- 36.1 pg mL(-1); P < 0.001) and AD (18.0 +/- 6.4 pg mL(-1); P < 0.001). Among patients with SSc, there were no differences in serum CCL13 levels between limited cutaneous SSc and diffuse cutaneous SSc. In a longitudinal study, CCL13 levels were generally unchanged during the follow-up. Conclusions Serum CCL13 was specifically increased in patients with SSc, but not in patients with SLE, DM or AD or in healthy controls. CCL13 could be a promising serological marker for SSc.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"The British journal of dermatology, 162(2), pp.332-336; 2010","subitem_description_type":"Other"}]},"item_2_relation_11":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"19747218","subitem_relation_type_select":"PMID"}}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1111/j.1365-2133.2009.09507.x","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Authors 2010. This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in British Journal of Dermatology, 162(2), pp.332-336. http://dx.doi.org/10.1111/j.1365-2133.2009.09507.x"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00574479","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00070963","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13652133","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yanaba, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshizaki, Ayumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Muroi, Eiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hara, Toshihide"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogawa, Fumihide"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu, Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hasegawa, Minoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujimoto, Manabu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takehara, Kazuhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Shinichi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"BJD162_332.pdf","filesize":[{"value":"8.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BJD162_332.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/15224/files/BJD162_332.pdf"},"version_id":"c9f59e2a-726c-46c8-a1d4-e0b589db0dc4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CCL13","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemokine","subitem_subject_scheme":"Other"},{"subitem_subject":"Enzyme-linked immunosorbent assay","subitem_subject_scheme":"Other"},{"subitem_subject":"Systemic sclerosis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"CCL13 is a promising diagnostic marker for systemic sclerosis.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"CCL13 is a promising diagnostic marker for systemic sclerosis."}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-03-07"},"publish_date":"2011-03-07","publish_status":"0","recid":"15224","relation_version_is_last":true,"title":["CCL13 is a promising diagnostic marker for systemic sclerosis."],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-05-15T19:06:10.229212+00:00"}