@article{oai:nagasaki-u.repo.nii.ac.jp:00015256, author = {Izumikawa, Koichi and Nakano, Ken and Kurihara, Shintaro and Imamura, Yoshifumi and Yamamoto, Kazuko and Miyazaki, Taiga and Sakamoto, Noriho and Seki, Masafumi and Ishimatsu, Yuji and Kakeya, Hiroshi and Yamamoto, Yoshihiro and Yanagihara, Katsunori and Tsuchiya, Tomoshi and Yamasaki, Naoya and Tagawa, Tsutomu and Mukae, Hiroshi and Nagayasu, Takeshi and Kohno, Shigeru}, issue = {5}, journal = {Internal Medicine}, month = {}, note = {Diffuse alveolar hemorrhage (DAH) syndrome is potentially fatal. We encountered a nearly fatal case of DAH possibly due to intravenous itraconazole (ITCZ). A 53-year-old man with chronic pulmonary aspergillosis underwent pneumonectomy of the left lung 15 days prior to the onset of DAH, which was confirmed by bronchoalveloar lavage. The battery of diagnostic evaluations performed revealed no other positive etiological factor, leading to the diagnosis of DAH possibly induced by intravenous ITCZ with a positive drug lymphocyte stimulation test. The patient did not respond to pulse methylprednisolone therapy, but responded dramatically to direct hemoperfusion using a polymyxin B-immobilized fiber column (PMX) therapy., Internal Medicine, 49(5), pp.497-500; 2010}, pages = {497--500}, title = {Diffuse Alveolar Hemorrhage following Itraconazole Injection}, volume = {49}, year = {2010} }