@article{oai:nagasaki-u.repo.nii.ac.jp:00015263, author = {Miyazaki, Taiga and Yamauchi, Shunsuke and Inamine, Tatsuo and Nagayoshi, Yosuke and Saijo, Tomomi and Izumikawa, Koichi and Seki, Masafumi and Kakeya, Hiroshi and Yamamoto, Yoshihiro and Yanagihara, Katsunori and Miyazaki, Yoshitsugu and Kohno, Shigeru}, issue = {4}, journal = {Antimicrobial agents and chemotherapy}, month = {Apr}, note = {A Candida glabrata calcineurin mutant exhibited increased susceptibility to both azole antifungal and cell wall-damaging agents and was also attenuated in virulence. Although a mutant lacking the downstream transcription factor Crz1 displayed a cell wall-associated phenotype intermediate to that of the calcineurin mutant and was modestly attenuated in virulence, it did not show increased azole susceptibility. These results suggest that calcineurin regulates both Crz1-dependent and -independent pathways depending on the type of stress., Antimicrobial agents and chemotherapy, 54(4), pp.1639-1643; 2010}, pages = {1639--1643}, title = {Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.}, volume = {54}, year = {2010} }