{"created":"2023-05-15T16:40:52.071603+00:00","id":15298,"links":{},"metadata":{"_buckets":{"deposit":"d950bf37-ed7d-4219-9da2-0277a9181106"},"_deposit":{"created_by":2,"id":"15298","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"15298"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00015298","sets":["8:9"]},"author_link":["56532","56539","56540","56538","56536","56531","56537","56529","56534","56543","56530","56542","56533","56535","56541"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"1323","bibliographicPageStart":"1317","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"Oncology Reports"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The number and ratio of both HBsAg- and HCV Abnegative hepatocellular carcinoma (HCC-nonBC) cases have been steadily increasing in Japan. The aim of this study was to examine the frequency of detection of HCC-nonBC by screening methods and to elucidate the clinical characteristics of HCC-nonBC compared with those of hepatitis C and/or B virus-associated HCC (HCC-virus). We recruited 624 patients with HCC who were diagnosed between 1982 and 2007 at the Department of Gastroenterology and Hepatology, Nagasaki University Hospital. They were categorized into 2 groups as follows: i) 550 were included in the HCC-virus group: positive for HBsAg and/or positive for HCV Ab, and ii) 74 were included in the HCC-nonBC group: negative for both HBsAg and HCV Ab. The follow-up patterns until the initial detection of HCC and the survival rates were analyzed and compared between the 2 groups. Multivariate analysis identified follow-up, alcohol consumption, albumin level, total bilirubin level, α-fetoprotein (AFP) level, and tumor-node-metastasis (TNM) stage as independent and significant risk factors for prognosis. Among the 397 patients with HCC in TNM stage I or II, multivariate analysis identified the cause of liver disease, gender, Child-Pugh score, serum albumin level and TNM stage as independent and significant risk factors for prognosis. We reported that the poor prognoses of patients with HCC-nonBC were attributable to its late detection in an advanced condition due to the absence of a surveillance system for the early detection of HCC. However, in early-stage patients, patients with HCC-nonBC showed significantly better prognosis than those in the HCC-virus group.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Oncology Reports, 23(5), pp.1317-1323; 2010","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Spandidos Publications"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3892/or-00000766","subitem_relation_type_select":"DOI"}}]},"item_2_relation_42":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://hdl.handle.net/10069/25126"}]}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11016405","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1021335X","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Akahoshi, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taura, Naota"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ichikawa, Tatsuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyaaki, Hisamitsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Akiyama, Motohisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miuma, Satoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ozawa, Eisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeshita, Shigeyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Muraoka, Toru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuzaki, Toshihisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohtani, Masashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Isomoto, Hajime"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumoto, Takehiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeshima, Fuminao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakao, Kazuhiko"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"OncRep23_1317.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"OncRep23_1317.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/15298/files/OncRep23_1317.pdf"},"version_id":"dd5f0ea0-dc39-4e6c-b556-50fd26fe586f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Hepatocellular carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"Viral hepatitis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Differences in prognostic factors according to viral status in patients with hepatocellular carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Differences in prognostic factors according to viral status in patients with hepatocellular carcinoma"}]},"item_type_id":"2","owner":"2","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-06-06"},"publish_date":"2011-06-06","publish_status":"0","recid":"15298","relation_version_is_last":true,"title":["Differences in prognostic factors according to viral status in patients with hepatocellular carcinoma"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-17T21:21:11.866855+00:00"}