@article{oai:nagasaki-u.repo.nii.ac.jp:00001575,
 author = {MAEDA, Mitsuko and KAWASAKI, Koichi and TAGUCHI, Takeo and KOBAYASHI, Yoshiro and YAMAMOTO, Yoshihiro and SHIMOKAWA, Kazuhiro and TAKAHASHI, Masakatsu and NAKAO, Kaoru and KANETO, Hiroshi},
 issue = {8},
 journal = {Chemical & Pharmaceutical Bulletin},
 month = {Aug},
 note = {Fluorinated analogs of Leu-enkephalin were synthesized by the solution method and the solid-phase method. The synthetic peptides were examined for opioid activities on mouse vas deferens and guinea pig ileum. Among the synthetic peptides, [D-Ala2, Leu(F3)(2R, 4S)5]enkephalin and [D-Ala2, Leu(F3)(2S, 4R)5]enkephalin exhibited potent opioid activity, and [Leu(F3)(2S, 4R)5]enkephalin exhibited high δ-receptor selectivity., Chemical & Pharmaceutical Bulletin, 42(8), pp.1658-1662; 1994},
 pages = {1658--1662},
 title = {Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5.},
 volume = {42},
 year = {1994}
}