{"created":"2023-05-15T16:30:26.776878+00:00","id":1575,"links":{},"metadata":{"_buckets":{"deposit":"a87f6287-1586-4f4d-b0dd-18b260a41463"},"_deposit":{"created_by":2,"id":"1575","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"1575"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00001575","sets":["73:74"]},"author_link":["7586","7583","7584","7581","7585","7582","7578","7580","7579"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1994-08-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"1662","bibliographicPageStart":"1658","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"Chemical & Pharmaceutical Bulletin"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fluorinated analogs of Leu-enkephalin were synthesized by the solution method and the solid-phase method. The synthetic peptides were examined for opioid activities on mouse vas deferens and guinea pig ileum. Among the synthetic peptides, [D-Ala2, Leu(F3)(2R, 4S)5]enkephalin and [D-Ala2, Leu(F3)(2S, 4R)5]enkephalin exhibited potent opioid activity, and [Leu(F3)(2S, 4R)5]enkephalin exhibited high δ-receptor selectivity.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Chemical & Pharmaceutical Bulletin, 42(8), pp.1658-1662; 1994","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本薬学会"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/cpb.42.1658","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c The Pharmaceutical Society of Japan"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00602100","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00092363","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13475223","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Pharmaceutical Society of Japan"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MAEDA, Mitsuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAWASAKI, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAGUCHI, Takeo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KOBAYASHI, Yoshiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMAMOTO, Yoshihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SHIMOKAWA, Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Masakatsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAKAO, Kaoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KANETO, Hiroshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"CPB42_1658.pdf","filesize":[{"value":"826.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"CPB42_1658.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/1575/files/CPB42_1658.pdf"},"version_id":"2e5d61fd-3998-4ffa-a9bc-ade79af472a6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"opioid peptide","subitem_subject_scheme":"Other"},{"subitem_subject":"fluorinated amino acid","subitem_subject_scheme":"Other"},{"subitem_subject":"enkephalin","subitem_subject_scheme":"Other"},{"subitem_subject":"opioid receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"mouse vas deferens","subitem_subject_scheme":"Other"},{"subitem_subject":"guinea pig ileum","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5."}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-02-21"},"publish_date":"2019-02-21","publish_status":"0","recid":"1575","relation_version_is_last":true,"title":["Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5."],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:00:02.001275+00:00"}