{"created":"2023-05-15T16:30:27.065429+00:00","id":1582,"links":{},"metadata":{"_buckets":{"deposit":"8963ed52-ae58-497f-b630-15a3209c3162"},"_deposit":{"created_by":2,"id":"1582","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"1582"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00001582","sets":["73:74"]},"author_link":["7618","7619","7620"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"361","bibliographicPageStart":"357","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"Journal of Pharmacobio-Dynamics"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In mice, both swimming-stress induced analgesia (SW-SIA) and clonidine (CLO) analgesia were dose dependently antagonized by yohimbine, an α2-adrenoceptor antagonist, but not by naloxone, an opioid μ-antagonist. SW-SIA was potentiated by subanalgesic dose of CLO, and CLO analgesia was enhanced by SW-SIA. Animals tolerant to CLO analgesia were tolerant to SW-SIA, in contrast, CLO analgesia was potentiated in SW-SIA tolerant mice. Thus, SW-SIA and CLO analgesia partially share a common α2-adrenergic-dependent mechanism, for their production.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Journal of Pharmacobio-Dynamics, 14(6), pp.357-361; 1991","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本薬学会"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/bpb1978.14.357","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c The Pharmaceutical Society of Japan"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00704585","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386846X","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"18811353","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Pharmaceutical Society of Japan"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TOKUYAMA, Shogo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Masakatsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KANETO, Hiroshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"JPD14_357.pdf","filesize":[{"value":"450.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JPD14_357.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/1582/files/JPD14_357.pdf"},"version_id":"fd7b805b-07ba-46aa-98ea-f81780383e31"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"α2-adrenoceptor","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Participation of an α2-mediated mechanism in the production of forced swimming-stress induced analgesia in mice.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Participation of an α2-mediated mechanism in the production of forced swimming-stress induced analgesia in mice."}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-02-21"},"publish_date":"2019-02-21","publish_status":"0","recid":"1582","relation_version_is_last":true,"title":["Participation of an α2-mediated mechanism in the production of forced swimming-stress induced analgesia in mice."],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:59:51.959657+00:00"}