@article{oai:nagasaki-u.repo.nii.ac.jp:00015924,
 author = {Yoshioka, Daisuke and Sakamoto, Noriho and Ishimatsu, Yuji and Kakugawa, Tomoyuki and Ishii, Hiroshi and Mukae, Hiroshi and Kadota, Jun-ichi and Kohno, Shigeru},
 issue = {14},
 journal = {Internal Medicine},
 month = {},
 note = {A 46-year-old man was referred to our hospital with hemoptysis. He had been diagnosed with chronic sinusitis since childhood, but had received no treatment. Chest CT showed a diffuse centrilobular granular shadow and thickened bronchial walls. Otitis media and decreased spermatic motor ability were identified. In addition, electron microscopy of a biopsy specimen of the nasal mucosa showed a deficiency of inner dynein. Based on these clinical findings, primary ciliary dyskinesia (PCD) was diagnosed and successfully treated with long-term, low-dose clarithromycin. Although the effects of macrolide therapy remain controversial, long-term treatment with low-dose clarithromycin might confer clinical benefits upon patients with PCD., Internal Medicine, 49(14), pp.1437-1440; 2010},
 pages = {1437--1440},
 title = {Primary Ciliary Dyskinesia that Responded to Long-Term, Low-Dose Clarithromycin},
 volume = {49},
 year = {2010}
}