@article{oai:nagasaki-u.repo.nii.ac.jp:00016366,
 author = {Nakamura, Shigeki and Yanagihara, Katsunori and Araki, Nobuko and Morinaga, Yoshitomo and Izumikawa, Koichi and Seki, Masafumi and Kakeya, Hiroshi and Yamamoto, Yoshihiro and Kamihira, Shimeru and Kohno, Shigeru},
 issue = {3},
 journal = {International journal of antimicrobial agents},
 month = {Sep},
 note = {A novel murine model of non-typeable Haemophilus influenzae (NTHi) pneumonia was established. A plastic tube was inserted into the trachea 7 days before bacterial inoculation. Numbers of NTHi recovered from the lungs and trachea were determined for 7 days. Histologically, bronchioles and adjacent alveoli in the intubation group were filled with numerous inflammatory cells. The efficacy of sitafloxacin was compared with ciprofloxacin using the new murine pneumonia model. The data suggest that sitafloxacin displays equivalent efficacy to ciprofloxacin against H. influenzae pneumonia. This new murine NTHi pneumonia model appears useful not only for in vivo evaluation of antibiotics but also for analysis of the pathogenesis of H. influenzae pneumonia., International Journal of Antimicrobial Agents, 34(3), pp.210-214; 2009},
 pages = {210--214},
 title = {In vivo efficacy of sitafloxacin in a new murine model of non-typeable Haemophilus influenzae pneumonia by sterile intratracheal tube.},
 volume = {34},
 year = {2009}
}