@article{oai:nagasaki-u.repo.nii.ac.jp:00016435,
 author = {Takazono, Takahiro and Izumikawa, Koichi and Mihara, Tomo and Kosai, Kosuke and Saijo, Tomomi and Imamura, Yoshifumi and Miyazaki, Taiga and Seki, Masafumi and Kakeya, Hiroshi and Yamamoto, Yoshihiro and Yanagihara, Katsunori and Kohno, Shigeru},
 issue = {8},
 journal = {Antimicrobial agents and chemotherapy},
 month = {Aug},
 note = {Targeted intrapulmonary delivery of drugs may reduce systemic toxicity and improve treatment efficacy. In the current study, we evaluated the effects of a combination treatment consisting of inhalation of aerosolized liposomal amphotericin B (L-AMB) with intraperitoneal administration of micafungin (MCFG) against murine invasive pulmonary aspergillosis. The combination of aerosolized L-AMB with intraperitoneal MCFG significantly improved the survival rate, and the fungal burdens and histopathology findings after this treatment were superior to those of the control and both monotherapy groups., Antimicrobial agents and chemotherapy, 53(8), pp.3508-3510; 2009},
 pages = {3508--3510},
 title = {Efficacy of combination antifungal therapy with intraperitoneally administered micafungin and aerosolized liposomal amphotericin B against murine invasive pulmonary aspergillosis.},
 volume = {53},
 year = {2009}
}