@article{oai:nagasaki-u.repo.nii.ac.jp:00016492,
 author = {Nakajima, Yasuo and Aoki, Yoshiki and Sakamoto, Makoto and Suenaga, Osamu and Katamine, Daisuke},
 issue = {3, 4},
 journal = {日本熱帯医学会雑誌, Japanese journal of tropical medicine and hygiene},
 month = {Dec},
 note = {済州島糸状虫浸淫地のミクロフィラリア(mf.)陽性者の住居で採集した，自然感染Aedestogoiより得た感染幼虫を，鼠径部皮下に注射して3頭のイエネコにChe-ju strainのB. malayiを感染させることに成功した。その感染ネコを，恒温室内で累代飼育中のAe. togoi (Nagasaki strain)に吸血させて得た感染幼虫を接種し、9頭のネコに第2代の感染を成立させた。Ae. togoi を用い2頭の，Ae. aegypti (Liverpool strain)を用い4頭のネコに，皮下接種により第3代の感染を成立させた。接種後mf.を末梢血に検出するまでに91～131日を要した。末梢血中のmf.数は感染の成立したネコの1/3～2/3では，次第に増加した。従ってネコはChe-ju strainのB. malayiの比較的好適な宿主と考えられる。Che-ju strainのmf.はヒトではperiodic typeであるが，ネコでは夜間出現性が顕著でなく，昼間にもかなり末梢血中に認められ， sub-periodicの傾向を示した。生前或は剖検時mf.が検出された8頭のうち、2頭の腎周囲脂肪組織より成虫が回収された。成虫の局在部位は， 接種された虫体の体内部リンパ管への移動を示唆し，その為，剖検時成虫の検出が困難となると思われる。累代飼育中のAe. togoiのB. malayi感染幼虫による感染率は69.3%で，感染蚊1個当たりの平均保有感染幼虫数は， 5.8隻であった。従ってAe. togoiはB. malayiのlaboratory vectorとして用い得る。Armigeres subalbatusはB. malayi に感受性を示さなかったが，近似種のB. pahangiは両種の蚊にて感染幼虫まで発育した。, Che-ju strain of B. malayi was successfully transmitted to three domestic cats by subcutaneous injection of infective-stage larvae obtained from naturally-infected Ae. togoi. The second generation of the strain of B. malayi was established in nine cats which had been inoculated subcutaneously with the infective larvae developed in laboratory-bred Nagasaki strain of Ae. togoi. The third generation was built up by subcutaneous inoculation in two cats through Ae. togoi and four cats through Liverpool strain of Ae. aegypti. The prepatent periods were 91-131 days. The microfilaria counts in the peripheral blood gradually increased in one third to two thirds of successfully transmitted cats. The microfilariae of Che-ju strain exhibited a sub-periodic tendency in the cat. The average infection rate of laboratory-bred Nagasaki strain of Ae. togoi was 69.3% with infective larvae of B. malayi. The mean number of larvae per mosquito was 5.8 with the infective larvae. Nagasaki strain of Ar. subalbatus was not susceptible to B. malayi infection. B. pahangi developed to the infective form in both Ae. togoi and Ar. subalbatus., 日本熱帯医学会雑誌, vol.4(3, 4), pp.163-177; 1976},
 pages = {163--177},
 title = {STUDIES ON MALAYAN FILARIASIS IN CHE-JU IS., KOREA - 4 Experimental transmission of Brugia malayi (Che-ju strain) to domestic cats -},
 volume = {4},
 year = {1976}
}