@article{oai:nagasaki-u.repo.nii.ac.jp:00016512,
 author = {Senba, Masachika and Nakamura, Tsuyoshi and Itakura, Hideyo},
 issue = {1},
 journal = {日本熱帯医学会雑誌, Japanese journal of tropical medicine and hygiene},
 month = {Mar},
 note = {1964-1973年と1974-1983年の各年代におけるB型肝炎表層抗原の陽性率を急性肝炎，慢性肝炎，肝硬変， 肝硬変に伴った肝細胞癌および肝細胞癌の組織を長崎大学病院の剖検肝臓422例を使用して検索した。B型肝炎表層抗原は急性肝炎の17例の全て陰性であり， 慢性肝炎および肝細胞癌の例では1964-1983年の差は小さかった。また，B型肝炎表層抗原は肝硬変および肝硬変に伴った肝細胞癌の例で減少していた。しかしながら，2年代におけるB型肝炎表層抗原の減少は肝硬変に伴った肝細胞癌の例では有意であったが，肝硬変では有意ではなかった。このことは最近の10年間ではB型肝炎ウイルスによる輸血後肝炎がなくなったためと思われた。, Histopathological analysis was carried out to determine whether hepatitis B surface antigen with the autopsy diagnoses of chronic hepatitis, cirrhosis and/or hepatocellular carcinoma declined between the 1964-1973 and 1974-1983 decades. In this study, the liver specimens from 422 autopsy cases at Nagasaki University Hospital were used. All of the 17 cases of acute hepatitis were hepatitis B surface antigen negative. Hepatitis B surface antigen positive rates in chronic hepatitis and hepatocellular carcinoma showed minor changes during 1964-1983. On the other hand, proportions of hepatitis B surfce antigen carriers in cirrhosis and cirrhosis with hepatocellular carcinoma in the recent decade 1974-1983 were found to decrease compared to the last decade 1964-1973. However, the difference of the hepatitis B surface antigen positive rates in cirrhosis with hepatocellular carcinoma between the 2 periods was marginally significant, but not significant in cirrhosis. A possible explanation may be that many cases of posttransfusion hepatitis in the latter decade are not caused by hepatitis B virus., 日本熱帯医学会雑誌, vol.15(1), pp.25-28; 1987},
 pages = {25--28},
 title = {DECREASE TREND IN PROPORTIONS OF HEPATITIS B SURFACE ANTIGEN CARRIER IN CHRONIC HEPATITIS, CIRRHOSIS AND CIRRHOSIS WITH HEPATOCELLULAR CARCINOMA},
 volume = {15},
 year = {1987}
}