{"created":"2023-05-15T16:41:46.702498+00:00","id":16529,"links":{},"metadata":{"_buckets":{"deposit":"b207f1f7-4279-4f60-88d0-9c3f0b788bc2"},"_deposit":{"created_by":2,"id":"16529","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"16529"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00016529","sets":["35:36"]},"author_link":["63065","63067","63062","63064","63061","63069","63063","63066","63068","63060"],"item_2_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"アフリカ風土病型カポシ肉腫　―9例における病理組織学的検討ならびにフローサイトメトリー法による核DNA量解析―"}]},"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-06-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"134","bibliographicPageStart":"129","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"日本熱帯医学会雑誌"},{"bibliographic_title":"Japanese journal of tropical medicine and hygiene","bibliographic_titleLang":"en"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"カポシ肉腫(Kaposi's sarcoma，K S)は一般には，欧米古典型，アフリカ風土病型，AIDS関連型，その他の免疫不全型の4型に大別され，さらにアフリカ風土病型KSは，発生部位により皮膚型とリンパ節型に分けられている。それぞれの型において若干の病態的な差異が認められているが，その組織発生を含め本態は未だ不明のことが多い。最近ではフローサイトメトリー(FCM)法による核DNA量解析が腫瘍，あるいは腫瘍様病変の悪性度評価に，広く用いられている。今回9例のアフリカ風土病型KSにおいて，病理組織学的検討，ならびにホルマリン固定，パラフィン包埋プロックを用いたFCM法による，核DNA量解析を行った。組織学的には次の3型に分けられた。すなわち肉芽組織類似型(1例)，血管腫あるいは血管肉腫類似型(4例)と紡錘形細胞型(4例)である。これら3型においては，細胞密度や細胞異型に程度の差はあるものの，紡錘形細胞の増殖という点からは，基本的な差は見られなかった。核分裂像も目立たなかった。FCM法による核DNA量では，全例がdiploidを示しており， aneuploid例は見られなかった。これらの結果より，アフリカ風土病型KSは悪性腫瘍というより，むしろless aggressiveな病変であると思われた。","subitem_description_type":"Abstract"},{"subitem_description":"Flow cytometric DNA analysis using formalin-fixed, paraffin-embedded tissues were performed on nine cases of African endemic-type Kaposi's sarcoma (KS). Histologically, these cases were classified into the following three types; granulation tissue like (one case), angioma/angiosarcoma-like (four cases) and spindle cell (four cases). Although these three types showed a variety of cellularity and cellular atypism, there were no fundamental differences in the view point of proliferation of spindle cell. Mitotic figures were not prominent. All cases were exclusively diploid and lacked an aneuploid population by flow cytometric measurement of DNA content. These results suggest that African endemic-type KS is a less aggressive disease rather than a malignant neoplasm.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"日本熱帯医学会雑誌, vol.20(2), pp.129-134; 1992","subitem_description_type":"Other"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"63065","nameIdentifierScheme":"WEKO"}],"names":[{"name":"江藤, 秀顕"}]},{"nameIdentifiers":[{"nameIdentifier":"63066","nameIdentifierScheme":"WEKO"}],"names":[{"name":"鳥山, 寛"}]},{"nameIdentifiers":[{"nameIdentifier":"63067","nameIdentifierScheme":"WEKO"}],"names":[{"name":"板倉, 英世"}]},{"nameIdentifiers":[{"nameIdentifier":"63068","nameIdentifierScheme":"WEKO"}],"names":[{"name":"田川, 泰"}]},{"nameIdentifiers":[{"nameIdentifier":"63069","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kamidigo, Noah O."}]}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本熱帯医学会"}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Japanese Society of Tropical Medicine"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00196023","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03042146","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Japanese Society of Tropical Medicine"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Eto, Hideaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Toriyama, Kan"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Itakura, Hideyo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tagawa, Yutaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kamidigo, Noah O."}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"JJTMH20_129.pdf","filesize":[{"value":"510.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JJTMH20_129.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/16529/files/JJTMH20_129.pdf"},"version_id":"bd5094c0-5cf6-4c9d-aa0b-e4abb6fe43c9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"AFRICAN ENDEMIC-TYPE KAPOSI'S SARCOMA - A HISTOPATHOLOGIC STUDY AND FLOW CYTOMETRIC DNA ANALYSIS OF NINE CASES -","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"AFRICAN ENDEMIC-TYPE KAPOSI'S SARCOMA - A HISTOPATHOLOGIC STUDY AND FLOW CYTOMETRIC DNA ANALYSIS OF NINE CASES -"}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-11-17"},"publish_date":"2009-11-17","publish_status":"0","recid":"16529","relation_version_is_last":true,"title":["AFRICAN ENDEMIC-TYPE KAPOSI'S SARCOMA - A HISTOPATHOLOGIC STUDY AND FLOW CYTOMETRIC DNA ANALYSIS OF NINE CASES -"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-17T20:43:43.329905+00:00"}