@article{oai:nagasaki-u.repo.nii.ac.jp:00016544, author = {Silva-Tahat, Mary Rose Agnes and Ichinose, Akitoyo and Uemura, Haruki and Kanbara, Hiroji}, issue = {1}, journal = {日本熱帯医学会雑誌, Japanese journal of tropical medicine and hygiene}, month = {Mar}, note = {Pararosaniline-induced akinetoplastic clones of Tmpanosoma evansi which lack DAPI-stainable kDNA network were characterized by scanning electron microscopy. Independent batches of akinetoplastic parasites from two passages in mice were observed to have similarities with parental kinetoplastic strain with respect to shape, form, and pleomorphism. The marked difference in surface topography was noted between the wildtype and the mutant as unique concavities on the cell surface of the latter. These concavities are variable in size, number and extent and may be inheritable. In addition, akinetoplastic cells were found to undergo active longitudinal binary fission and filopodia formation as reported by others. These observations suggest that the kDNA-deficient mutants of T. evansi have maintained their basic functions of cell division and infectivity and, therefore, the concavities on their surface are not detrimental to their existence., 日本熱帯医学会雑誌, vol.23(1), pp.9-13; 1995}, pages = {9--13}, title = {TRYPANOSOMA EVANSI: UNIQUE CONCAVITIES ON THE SURFACE MEMBRANE OF PARAROSANILINE-INDUCED AKINETOPLASTIC CLONES AS REVEALED BY SCANNING ELECTRON MICROSCOPY}, volume = {23}, year = {1995} }