@article{oai:nagasaki-u.repo.nii.ac.jp:00001671,
 author = {Fukuda, Tsutomu and Komure, Minoru and Onodera, Gen and Kimura, Masanari and Iwao, Masatomo},
 issue = {2},
 journal = {HETEROCYCLES},
 month = {Apr},
 note = {A method for the synthesis of 4,5-disubstituted pyrano[3,4-b]pyrrol-7-(1H)-ones has been developed in this study. The key reactions involved are the Sonogashira?Hagihara cross-coupling of methyl N-benzenesulfonyl-3-bromo-1H-pyrrole-2-carboxylate with terminal alkynes, followed by the iodine-mediated cyclization of 3-alkynylated N-benzenesulfonyl-1H-pyrrole-2-carboxylates. The thus-obtained 5-substituted 4-iodopyrano[3,4-b]pyrrol-7(1H)-ones could be converted to 4,5-disubstituted pyrano[3,4-b]pyrrol-7(1H)-ones via the Suzuki?Miyaura or Sonogashira?Hagihara cross-coupling reactions., HETEROCYCLES, 97(2), pp.916-930; 2018},
 pages = {916--930},
 title = {Synthesis of 4,5-Disubstituted Pyrano[3,4-b]Pyrrol-7(1H)-ones via Sonogashira?Hagihara Cross-Coupling of N-Benzenesulfonyl-3-bromo-1H-pyrrole-2-carboxylate and Subsequent Iodine-mediated Cyclization},
 volume = {97},
 year = {2018}
}