{"created":"2023-05-15T16:42:28.923289+00:00","id":17505,"links":{},"metadata":{"_buckets":{"deposit":"e37475ee-3e97-4794-8118-e24d0c1d8930"},"_deposit":{"created_by":2,"id":"17505","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"17505"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00017505","sets":["10:11"]},"author_link":["69126","69129","69131","69127","69128","69130","69132"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"68","bibliographicPageStart":"61","bibliographicVolumeNumber":"158","bibliographic_titles":[{"bibliographic_title":"The Journal of surgical research"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND: The time-signal intensity curve (TIC) of the pancreas obtained from dynamic contrast-enhanced magnetic resonance imaging closely reflects the histological degree of pancreatic fibrosis. MATERIALS AND METHODS: Seventy-six patients who had undergone a pancreatic TIC analysis prior to receiving a pancreaticoduodenectomy for various reasons were subjected to a yearly monitoring with pancreatic TIC for the pancreatic remnants. The pancreatic TIC profiles were classified into 3 types: type I, indicating a normal pancreas without fibrosis; and types II and III indicating fibrotic pancreas. RESULTS: The preoperative pancreatic TICs were type-I in 51 patients, type-II in 20, and type-III in 5, and the corresponding pancreatic fibrosis ratios were proved histologically to be 4.1%, 13.3%, and 21.2%, respectively. The mean postoperative follow-up period was 40.2 mo. A type-I changed to type-II in 16 patients, by 32.3 mo after surgery. In these patients, the exocrine remnant pancreatic function was preserved at the time of TIC conversion, but it significantly deteriorated thereafter. Pancreatic anastomotic leakage was found to be a significant risk factor predisposing a patient to undergo postoperative TIC conversion. In contrast, a preoperative type-II or III showed a postoperative conversion to type-I or II in 6 patients. In this group, the exocrine pancreatic function was noted to show a good recovery. In 35 patients who had a type-I TIC throughout the study, the remnant pancreatic function was well maintained. CONCLUSIONS: Pancreatic TIC analysis has the ability to detect an early fibrotic change that precedes a functional deterioration of the pancreatic remnant after a pancreaticoduodenectomy. Following a pancreaticoduodenectomy, some patients show an improvement in pancreatic fibrosis, but they may also experience remnant pancreatic fibrosis when pancreatic anastomotic leakage occurs after surgery.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Journal of Surgical Research, 158(1), pp.61-68; 2010","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier B.V."}]},"item_2_relation_11":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"19215944","subitem_relation_type_select":"PMID"}}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.jss.2008.07.033","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c Copyright 2009 Elsevier B.V., All rights reserved."}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00708021","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"10958673","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tajima, Yoshitsugu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuroki, Tamotsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsuneoka, Noritsugu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Adachi, Tomohiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Isomoto, Ichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uetani, Masataka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kanematsu, Takashi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"JSR158_61.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JSR158_61.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/17505/files/JSR158_61.pdf"},"version_id":"31078216-4947-41d8-a6d3-abfab524cf95"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"pancreatic fibrosis","subitem_subject_scheme":"Other"},{"subitem_subject":"pancreatic function","subitem_subject_scheme":"Other"},{"subitem_subject":"remnant pancreas","subitem_subject_scheme":"Other"},{"subitem_subject":"pancreaticoduodenectomy","subitem_subject_scheme":"Other"},{"subitem_subject":"dynamic magnetic resonance imaging","subitem_subject_scheme":"Other"},{"subitem_subject":"time-signal intensity curve","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Monitoring Fibrosis of the Pancreatic Remnant After a Pancreaticoduodenectomy With Dynamic MRI.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Monitoring Fibrosis of the Pancreatic Remnant After a Pancreaticoduodenectomy With Dynamic MRI."}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-03-12"},"publish_date":"2009-03-12","publish_status":"0","recid":"17505","relation_version_is_last":true,"title":["Monitoring Fibrosis of the Pancreatic Remnant After a Pancreaticoduodenectomy With Dynamic MRI."],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:38:30.516772+00:00"}