@article{oai:nagasaki-u.repo.nii.ac.jp:00017769, author = {Nakamura, Shigeki and Yanagihara, Katsunori and Morinaga, Yoshitomo and Izumikawa, Koichi and Seki, Masafumi and Kakeya, Hiroshi and Yamamoto, Yoshihiro and Kamihira, Shimeru and Kohno, Shigeru}, issue = {3}, journal = {Journal of clinical microbiology}, month = {Mar}, note = {We established a real-time PCR assay with melting curve analysis to rapidly genotype quinolone resistance-determining regions (QRDRs) of gyrase A and topoisomerase IV genes in Haemophilus influenzae. This assay is a useful tool for the detection of fluoroquinolone resistance and for the early detection of preexisting QRDR mutations., Journal of Clinical Microbiology, 47(3), pp.781-784; 2009}, pages = {781--784}, title = {Melting curve analysis for rapid detection of topoisomerase gene mutations in Haemophilus influenzae.}, volume = {47}, year = {2009} }