@article{oai:nagasaki-u.repo.nii.ac.jp:00001789,
 author = {Hidaka, Masaaki and Eguchi, Susumu and Okuda, Koji and Beppu, Toru and Shirabe, Ken and Kondo, Kazuhiro and Takami, Yuko and Ohta, Masayuki and Shiraishi, Masayuki and Ueno, Shinichi and Nanashima, Atsushi and Noritomi, Tomoaki and Kitahara, Kenji and Fujioka, Hikaru},
 issue = {2},
 journal = {Annals of Surgery},
 month = {Jul},
 note = {Objective: The aim of the present study was to evaluate the value of anatomical resection
for HCC with micro-portal vascular invasion (vp1) between 2000 and 2010. Summary
of Background: Vascular invasion has been reported as a prognostic factor of liver
resection for hepatocellular carcinoma (HCC). Anatomical resection for HCC has resulted in optimum outcomes of eradicating intrahepatic micrometastases through the portal vein, but opposite results have also been reported. Methods: A clinical chart review was performed for 546 HCC patients with vp1. We retrospectively evaluated the recurrence-free survival (RFS) between anatomical (AR)and non-anatomical resection (NAR). The site of recurrence was also compared between these groups. The influence of AR on the overall survival (OS) and RFS rates was analyzed in patients selected by propensity score matching, and the prognostic factors were identified.
Results: A total of 546 patients were enrolled, including 422 in the AR group and 124 in the NAR group. There was no difference in the 5-year OS and RFS rates between the two groups. Local recurrence was significantly more frequent in the NAR group than in the AR group. In a multivariate analysis, hepatitis C (HCV), PIVKAII ?380 mAU/ml, tumor diameter ?5 cm and ?70 years of age were significant predictors of a poor RFS after liver
resection. There were no significant differences in the OS or RFS between the AR and NAR groups by a propensity score-matched analysis. Conclusion: Although local recurrence around the resection site was suppressed by AR, AR for HCC with vp1 did not influence the RFS or OS rates after hepatectomy in the modern era., Annals of Surgery, 271(2), pp.339-346; 2020},
 pages = {339--346},
 title = {Impact of Anatomical Resection for Hepatocellular Carcinoma With Microportal Invasion (vp1): A Multi-institutional Study by the Kyushu Study Group of Liver Surgery},
 volume = {271},
 year = {2018}
}