@article{oai:nagasaki-u.repo.nii.ac.jp:00017989, author = {Yoshimine, Hiroyuki and Oishi, Kazunori and Mubiru, Francis and Nalwoga, Hawa and Takahashi, Hidehiko and Amano, Hideaki and Ombasi, Philip and Watanabe, Kiwao and Joloba, Moses and Aisu, Thomas and Ahmed, Kamruddin and Shimada, Masaaki and Mugerwa, Roy and Nagatake, Roy}, issue = {3}, journal = {American Journal of Tropical Medicine and Hygiene}, month = {May}, note = {A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short-term parenteral ampicillin followed by oral amoxicillin for these patients in relation to HIV-status. We demonstrated a very high prevalence (75%) of HIV-1 infection. No significant difference was observed with respect to age, gender, prior antibiotic usage, symptoms, laboratory data or bacterial etiology between HIV-1-infected and HIV-uninfected CAP patients. Most strains of Streptococcus pneumoniae (n = 19) and Haemophilus influenzae (n = 8) isolated from HIV-1-infected patients were penicillin-resistant (95%) and beta-lactamase producing (75%) strains, respectively. A high percentage of good clinical response was found in both HIV-1-infected (81%) and HIV-uninfected (86%) among 39 patients with CAP due to a defined bacterial pathogen. These data support the use of short-term parenteral ampicillin for patients with bacterial CAP irrespective of HIV-status., American Journal of Tropical Medicine and Hygiene, 64(3), pp.172-177; 2001}, pages = {172--177}, title = {Community-acquired pneumonia in Ugandan adults: short-term parenteral ampicillin therapy for bacterial pneumonia}, volume = {64}, year = {2001} }