@article{oai:nagasaki-u.repo.nii.ac.jp:00018289, author = {Yamaguchi, Tomohiro and Fukuda, Tsutomu and Ishibashi, Fumito and Iwao, Masatomo}, issue = {22}, journal = {Tetrahedron Letters}, month = {May}, note = {The first total synthesis of lamellarin α 20-sulfate (1), a selective inhibitor of HIV-1 integrase, has been completed. The lamellarin α core in which 13-OH and 20-OH were differentially protected by isopropyl and benzyl groups, respectively, was constructed by using Hinsberg-type pyrrole synthesis and Suzuki-Miyaura coupling as the key reactions. The 20-sulfate was prepared by a sequence including debenzylation of 20-OBn, 2,2,2-trichloroethylsulfation of the resulting 20-OH, deprotection of 13-Oi-Pr, and final reductive cleavage of the 2,2,2-trichloroethyl ester., Tetrahedron Letters, 47(22), pp.3755-3757;2006}, pages = {3755--3757}, title = {The first total synthesis of lamellarin α 20-sulfate, a selective inhibitor of HIV-1 integrase}, volume = {47}, year = {2006} }