{"created":"2023-05-15T16:43:05.031304+00:00","id":18289,"links":{},"metadata":{"_buckets":{"deposit":"eb069ccf-a6b9-4c79-9320-75983abd5042"},"_deposit":{"created_by":2,"id":"18289","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"18289"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00018289","sets":["14:21"]},"author_link":["73036","73034","73033","73035"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-05-29","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"22","bibliographicPageEnd":"3757","bibliographicPageStart":"3755","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"Tetrahedron Letters"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The first total synthesis of lamellarin α 20-sulfate (1), a selective inhibitor of HIV-1 integrase, has been completed. The lamellarin α core in which 13-OH and 20-OH were differentially protected by isopropyl and benzyl groups, respectively, was constructed by using Hinsberg-type pyrrole synthesis and Suzuki-Miyaura coupling as the key reactions. The 20-sulfate was prepared by a sequence including debenzylation of 20-OBn, 2,2,2-trichloroethylsulfation of the resulting 20-OH, deprotection of 13-Oi-Pr, and final reductive cleavage of the 2,2,2-trichloroethyl ester.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Tetrahedron Letters, 47(22), pp.3755-3757;2006","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Ltd."}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.tetlet.2006.03.121","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2006 Elsevier Ltd All rights reserved."}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00861801","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00404039","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamaguchi, Tomohiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Tsutomu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishibashi, Fumito"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwao, Masatomo"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"TetLet47_22_3755.pdf","filesize":[{"value":"200.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"TetLet47_22_3755.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/18289/files/TetLet47_22_3755.pdf"},"version_id":"7f1727b2-ce49-4532-9c65-11a257e1166e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HIV-1 integrase inhibitor","subitem_subject_scheme":"Other"},{"subitem_subject":"lamellarin","subitem_subject_scheme":"Other"},{"subitem_subject":"sulfate","subitem_subject_scheme":"Other"},{"subitem_subject":"Hinsberg reaction","subitem_subject_scheme":"Other"},{"subitem_subject":"Suzuki-Miyaura coupling","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The first total synthesis of lamellarin α 20-sulfate, a selective inhibitor of HIV-1 integrase","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The first total synthesis of lamellarin α 20-sulfate, a selective inhibitor of HIV-1 integrase"}]},"item_type_id":"2","owner":"2","path":["21"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-10-21"},"publish_date":"2008-10-21","publish_status":"0","recid":"18289","relation_version_is_last":true,"title":["The first total synthesis of lamellarin α 20-sulfate, a selective inhibitor of HIV-1 integrase"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:02:01.621302+00:00"}