{"created":"2023-05-15T16:43:05.717595+00:00","id":18305,"links":{},"metadata":{"_buckets":{"deposit":"3d96aa39-20ff-4772-96dc-08687e35a9c6"},"_deposit":{"created_by":2,"id":"18305","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"18305"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00018305","sets":["35:36"]},"author_link":["73125","73128","73126","73127","73124"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"42","bibliographicPageStart":"40","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"American Journal of Tropical Medicine and Hygiene"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The polymorphisms in the Plasmodium falciparum multidrug resistance 1 (pfmdr1) and P. falciparum chloroquine resistance transporter (pfcrt) genes, which are associated with chloroquine resistance, were examined in 48 P. falciparum isolates from uncomplicated malaria patients from the West Lombok District in Indonesia. The point mutation N86Y in pfmdr1 was present in 35.4% of the isolates and mutation K76T in pfcrt was found in all but one of the samples studied. Identified pfcrt haplotypes were mainly identical to the Papua New Guinea type SagtVMNT (42 of 48, 87.5%), and a few isolates had the Southeast Asia type CVIET (5 of 48, 10.4%). Moreover, one P. falciparum isolate harbored the K76N mutation, giving rise to the haplotype CVMNN, which was not previously reported in field isolates. Our findings suggest that chloroquine resistance in this area might have the same origin as in Papua New Guinea.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"American Journal of Tropical Medicine and Hygiene, 71(1), pp.40-42; 2004","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"American Society of Tropical Medicine and Hygiene"}]},"item_2_relation_11":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"15238686","subitem_relation_type_select":"PMID"}}]},"item_2_relation_42":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.ajtmh.org/cgi/content/abstract/71/1/40"}]}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2004 by The American Society of Tropical Medicine and Hygiene"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00521439","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00029637","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Huaman, Maria Cecilia"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshinaga, Kazumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suryanatha, Aan"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suarsana, Nyoman"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kanbara, Hiroji"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"ajtmh71_40.pdf","filesize":[{"value":"73.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ajtmh71_40.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/18305/files/ajtmh71_40.pdf"},"version_id":"98cb057d-4706-4307-96c3-1a9cc906408e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Short report: polymorphisms in the chloroquine resistance transporter gene in Plasmodium falciparum isolates from Lombok, Indonesia.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Short report: polymorphisms in the chloroquine resistance transporter gene in Plasmodium falciparum isolates from Lombok, Indonesia."}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-10-21"},"publish_date":"2008-10-21","publish_status":"0","recid":"18305","relation_version_is_last":true,"title":["Short report: polymorphisms in the chloroquine resistance transporter gene in Plasmodium falciparum isolates from Lombok, Indonesia."],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:01:20.850226+00:00"}