@article{oai:nagasaki-u.repo.nii.ac.jp:00019003, author = {中島, 憲一郎}, issue = {10}, journal = {分析化学, BUNSEKI KAGAKU}, month = {Oct}, note = {薬物の乱用は世界中で大きな社会問題を引き起こしている.乱用によるリスクから人々の健康を予防し,守るためには乱用薬物の分析法の開発と応用が重要である.一方,薬物の摂取を証明するには,血液や尿などの生体試料の分析が不可欠であるが,その中で,毛髪は長期にわたる摂取情報を知ることのできる貴重な試料といえる.毛髪分析の歴史は比較的新しいが,分析機器の発展に伴って,実用的で有用な分析法が開発されるようになり,現在では法中毒学あるいは臨床化学などの分野で大いに利用されるようになっている.本総説では,毛髪分析の歴史,意義などを解説するとともに,最近の分析例を紹介する., The abuse of drugs is increasing and causing serious social problems world wide. The development and application of analytical methods of drugs of abuse are very important for the prediction of and protection from the risk to human health. On the other hand, analyses of biological samples, such as blood and urine are requisite to elucidate the use of drugs. Among the biological matrices, hair is valuable and includes intake information of the drug for a long period. Because the history of hair analysis is relatively new, along with the development of analytical instruments, practical and valuable methods for analysis of drugs of abuse have been developed. Now, these methods have been utilized in such fields as forensic science and clinical chemistry. In this review, the history and significance of hair analysis are discussed, and recently reported application cases are introduced., 分析化学, 57(10), pp.783-799; 2008}, pages = {783--799}, title = {乱用薬物の毛髪分析}, volume = {57}, year = {2008} }