@article{oai:nagasaki-u.repo.nii.ac.jp:00001919,
 author = {Nakano, Jiro and Hashizume, Kaori and Fukushima, Takuya and Ueno, Kazumi and Matsuura, Emi and Ikio, Yuta and Ishii, Shun and Morishita, Satoru and Tanaka, Koji and Kusuba, Yoko},
 issue = {4},
 journal = {Integrative Cancer Therapies},
 month = {Oct},
 note = {Objective. This study aimed to conduct a meta-analysis to establish the effect of exercise interventions on physical symptoms, 
including fatigue, nausea/vomiting, pain, dyspnea, insomnia, loss of appetite, constipation, and diarrhea in cancer patients 
and survivors. Methods. We searched articles published before April 2017 using the following databases: Cochrane Library, 
PubMed/MEDLINE, CINAHL, Scopus, PEDro, Health & Medical Collection, and Psychology Database. Randomized controlled 
trials (RCTs) of exercise intervention in cancer patients, which evaluated cancer-related physical symptoms using the European 
Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30, were included. Symptom scale data were extracted for meta-analysis. Subgroup analyses were performed for exercise types (aerobic, resistance, and mixed exercise programs). Results. Of the 659 articles, 10 RCTs were included in the meta-analysis, of which the mean PEDro score was 5.43 (SD = 1.28). Fatigue, pain, dyspnea, and insomnia were significantly lower in the intervention group than in the 
control group at postintervention in cancer patients. However, exercise intervention did not promote or suppress nausea/
vomiting, loss of appetite, constipation, and diarrhea in cancer patients. The effect of exercise type on each symptom was 
not different. Conclusion. Exercise intervention was confirmed to improve fatigue, pain, and insomnia and might have reduced 
dyspnea in cancer patients. However, the benefits of exercise on nausea/vomiting, loss of appetite, constipation, and diarrhea 
were not shown in any exercise type. Further research is warranted to examine the effects of exercise interventions on 
physical symptoms in cancer patients., Integrative Cancer Therapies, 17(4), pp.1048-1058; 2018},
 pages = {1048--1058},
 title = {Effects of Aerobic and Resistance Exercises on Physical Symptoms in Cancer Patients: A Meta-analysis},
 volume = {17},
 year = {2018}
}