@article{oai:nagasaki-u.repo.nii.ac.jp:00019552, author = {Matsuo, Tatsuki and Nakashima, Eiji and Carter, Randolph L. and Neriishi, Kazuo and Mabuchi, Kiyohiko and Akiyama, Mitoshi and Shimaoka, Katsutaro and Kinoshita, Ken-Ichiro and Tomonaga, Masao and Ichimaru, Michito}, issue = {1}, journal = {Journal of radiation research}, month = {Mar}, note = {Adult T-cell leukemia (ATL), induced by human T-lymphotropic virus type-I (HTLV-I), is endemic in Nagasaki, Japan. To investigate the effects of atomic-bomb radiation on development of this specific type of leukemia, 6182 individuals in the Radiation Effects Research Foundation (RERE) Adult Health Study sample in Hiroshima and Nagasaki were examined for positive rate of HTLV-I antibody. Several lymphocyte parameters were also studied for 70 antibody-positive subjects in Nagasaki. The HTLV-I antibody-positive rate was higher in Nagasaki (6.36%) than in Hiroshima (0.79%) and significantly increased with increasing age, but no association was observed with radiation dose. Whether relationship existed between antibody titer levels and radiation dose among antibody-positive subjects was not clear. The frequency of abnormal lymphocytes tended to be higher in antibody-positive subjects than in antibody-negative subjects, and higher in females than in males regardless of radiation dose. Whether relationship existed between antibody titer levels and radiation dose among antibody-positive subjects was not clear. The frequency of abnormal lymphocytes tended to be higher in antibody-positive subjects than in antibody-negative subjects, and higher in females than in males regardless of radiation dose . The lymphocyte count was lower in antibody-positive subjects than in antibody-negative subjects and lower in female than in male subjects. No evidence was found to suggest that atomic-bomb radiation plays an important role in HTLV-1 infection., Journal of radiation research. 1995, 36(1), p.8-16}, pages = {8--16}, title = {Anti-Human T-Lymphotropic Virus Type-I Antibodies in Atomic-Bomb Survivors}, volume = {36}, year = {1995} }