{"created":"2023-05-15T16:30:44.720007+00:00","id":1987,"links":{},"metadata":{"_buckets":{"deposit":"397eb6b1-032d-43d5-a159-52a66bb105c9"},"_deposit":{"created_by":2,"id":"1987","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"1987"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00001987","sets":["10:11"]},"author_link":["9159","9156","9161","9167","9165","9164","9158","9168","9160","9157","9166","9163","9162"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-06-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"42","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"Environmental Health and Preventive Medicine"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: We reported that human T cell leukemia virus 1 (HTLV-1) infection is positively associated with\natherosclerosis. Recent evidence has revealed a close association of periodontitis with atherosclerosis, endothelial dysfunction, and disruption of the microcirculation. However, the association between HTLV-1 and advanced\nperiodontitis has not been investigated to date. Since hematopoietic activity is closely linked to endothelial maintenance activity and is known to decline with age, we hypothesized that the state of hematopoietic activity\ninfluenced the association between HTLV-1 and advanced periodontitis in elderly participants.Methods: A cross-sectional study was performed including 822 elderly participants aged 60?99 years who\nparticipated in a dental health check-up. Advanced periodontitis was defined as a periodontal pocket ? 6.0 mm.Participants were classified as having low or high hematopoietic activity according to the median values of reticulocytes.\nResults: HTLV-1 infection was positively related to advanced periodontitis among participants with lower hematopoietic activity (lower reticulocyte count), but not among participants with higher hematopoietic activity(higher reticulocyte count). The adjusted odds ratio (95% confidence interval) considering potential confounding\nfactors was 1.92 (1.05?3.49) for participants with a lower reticulocyte count and 0.69 (0.35?1.36) for participants with\na higher reticulocyte count.Conclusions: Among elderly participants, the association between HTLV-1 infection and advanced periodontitis is influenced by hematopoietic activity. Since hematopoietic activity is associated with endothelial maintenance, these findings provide an efficient tool for clarifying the underlying mechanism of the progression of periodontitis among\nelderly participants.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Environmental Health and Preventive Medicine, 24(1), art.no.42; 2019","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central Ltd."}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/s12199-019-0796-6","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1342078X","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13474715","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimizu, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamanashi, Hirotomo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Masayasu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Furugen, Reiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwasaki, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayashida, Hideaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawasaki, Koji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kiyoura, Kairi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawashiri, Shin-Ya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Saito, Toshiyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawakami, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Takahiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"EHPM24_42.pdf","filesize":[{"value":"634.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"EHPM24_42.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/1987/files/EHPM24_42.pdf"},"version_id":"6b39695c-b450-46c7-b454-869bd6ba302f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Elderly participants","subitem_subject_scheme":"Other"},{"subitem_subject":"Hematopoietic activity","subitem_subject_scheme":"Other"},{"subitem_subject":"HTLV-1","subitem_subject_scheme":"Other"},{"subitem_subject":"Periodontitis","subitem_subject_scheme":"Other"},{"subitem_subject":"Reticulocyte","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Association between human T cell leukemia virus 1 (HTLV-1) infection and advanced periodontitis in relation to hematopoietic activity among elderly participants: a cross-sectional study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association between human T cell leukemia virus 1 (HTLV-1) infection and advanced periodontitis in relation to hematopoietic activity among elderly participants: a cross-sectional study"}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-07-02"},"publish_date":"2019-07-02","publish_status":"0","recid":"1987","relation_version_is_last":true,"title":["Association between human T cell leukemia virus 1 (HTLV-1) infection and advanced periodontitis in relation to hematopoietic activity among elderly participants: a cross-sectional study"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:54:27.960247+00:00"}