{"created":"2023-05-15T16:44:14.648696+00:00","id":19872,"links":{},"metadata":{"_buckets":{"deposit":"105a636f-0ad2-4f90-8be6-e35b9f1fd967"},"_deposit":{"created_by":2,"id":"19872","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"19872"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00019872","sets":["29:30:1713167819629:1380"]},"author_link":["83218","83217","83216"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1/4","bibliographicPageEnd":"8","bibliographicPageStart":"5","bibliographicVolumeNumber":"37","bibliographic_titles":[{"bibliographic_title":"Acta Medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Flow cytometric analysis of the cellular DNA content was conducted using paraffin-embedded liver tissues. Of the 488 cases examined, 413 (84.6%) cases were suitable for analysis. Of these, 296 (88.9%) were diploid and 37 (11.1%) were aneuploid. The ploidy pattern was unaffected by patients' sex and age. Long-term stored tissues were as suitable for analysis as short-term stored ones. An aneuploid pattern was more frequently found in hepatocellular carcinoma (HCC) (17/43,39.5%) than in non-neoplastic liver conditions (20/284,7.0%) (p<0.01). The ploidy pattern was determined to be one of the most important prognostic factors in HCC. An aneuploid pattern was also found in non-neoplastic liver conditions such as liver cirrhosis (LC) and chronic hepatitis caused by hepatitis virus (CH). It seems that the ploidy pattern and proliferative index (S+G2M fraction) do not always affect carcinogenesis in non-neoplastic liver conditions. Thus, flow cytometric analysis of the cellular DNA content using paraffin-embedded specimens is useful for determining the prognostic significance in HCC, although the significance is uncertain in non-neoplastic liver conditions.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta Medica Nagasakiensia. 1992, 37(1-4), p.5-8","subitem_description_type":"Other"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00005-P00008"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Omagari, Katsuhisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Imanishi, Takeo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Makiyama, Kazuya"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"acta37_01-04_02_t.pdf","filesize":[{"value":"468.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"acta37_01-04_02_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/19872/files/acta37_01-04_02_t.pdf"},"version_id":"d3252a6a-8df2-4035-a468-ba1b843b331e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Flow Cytometric Analysis of the Cellular DNA Content in Various Liver Diseases","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Flow Cytometric Analysis of the Cellular DNA Content in Various Liver Diseases"}]},"item_type_id":"3","owner":"2","path":["1380"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-06-20"},"publish_date":"2008-06-20","publish_status":"0","recid":"19872","relation_version_is_last":true,"title":["Flow Cytometric Analysis of the Cellular DNA Content in Various Liver Diseases"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2024-04-17T04:09:12.555885+00:00"}