@article{oai:nagasaki-u.repo.nii.ac.jp:00019894, author = {Tagawa, Yutaka and Nakazaki, Takayuki and Sawai, Terumitsu and Akama, Fumitaka and Jibiki, Masaaki and Yamaguchi, Shinya and Matsuo, Toshikazu and Tomita, Masao}, issue = {1/4}, journal = {Acta Medica Nagasakiensia}, month = {Dec}, note = {This study was performed for the evaluation of combined effects of OK-432 and anticancer agents on K562 cells in vitro. On the growth curve, an increase of cytocidl effects was not observed by co-operative action of OK-432 and Cisplatin, but such increase was found with OK-432 and VP-16. It was evident than there are the difference depending on the type of anticancer agent combined with OK-432. When this difference was investigated on the cell cycle, G2M phase accumulation was delayed with OK-432 and Cisplatin. On the other hand, this delay was not observed with OK-432 and VP-16. It was suggested that the degree of this G2M phase accumulation might affect the cytocidal effects on cancer cells., Acta Medica Nagasakiensia. 1992, 37(1-4), p.110-113}, pages = {110--113}, title = {A Study of Cytocidal Effects According to the Type of Anticancer Agent Combined with OK-432}, volume = {37}, year = {1992} }