| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-05-13 |
| タイトル |
|
|
タイトル |
Spheroid morphology of lung cancer cell lines correlates with oncological profiles |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Cancer spheroid |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Epithelial–mesenchymal transition |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Invasion ability |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Spheroid morphology |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Oishi, Kaido
Matsumoto, Keitaro
Hashimoto, Shintaro
Uchida, Fumitake
Hara, Ryosuke
Nishimuta, Masato
Matsumoto, Takamune
Iwatake, Mayumi
Tomoshige, Koichi
Doi, Ryoichiro
Machino Ryusuke
Obata, Tomohiro
Nagayasu, Takeshi
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We assessed the correlation between Multicellular tumor spheroids (MCTS) morphology and the oncological profile of lung cancer cells. MCTS were generated in five lung cancer cell lines and classified into Type–A MCTS, which showed strong aggregation, and Type–B MCTS, which showed weak aggregation. Drug resistance was higher in Type–A MCTS, and invasive ability was higher in Type–B MCTS. The oncologic profile of lung cancer cell lines correlated with MCTS morphology. MCTS morphology could thus be used in basic oncology research and as a clinical prognostic tool. Registry and the Registration No. of the study/trial Not Applicable. |
|
言語 |
en |
| 書誌情報 |
en : Discover Oncology
巻 16,
号 1,
p. art. no. 627,
発行日 2025-04-28
|
| 出版者 |
|
|
出版者 |
Springer Nature |
|
言語 |
ja |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2730-6011 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s12672-025-02132-y |
| 権利 |
|
|
権利情報 |
This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. |
|
言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Discover Oncology, 16(1), art. no. 627; 2025 |
|
言語 |
en |
DO16_627.pdf (1.5 MB)
